Which of the following statements about human African trypanosomiasis (HAT) is false? The nifurtimox and eflornithine combination therapy (NECT) fulfills all the important criteria... Which of the following statements about human African trypanosomiasis (HAT) is false? The nifurtimox and eflornithine combination therapy (NECT) fulfills all the important criteria of an ideal anti-parasitic drug. To evade the host immune system, the parasite uses a strategy known as antigenic variation. Trypanosoma brucei rhodesiense infections are generally sporadic and accidental infections. Trypanosoma brucei gambiense is responsible for the vast majority of HAT cases. The symptomology of HAT is similar for both Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense.
Understand the Problem
The question is asking to identify which statement regarding human African trypanosomiasis (HAT) is false among a set of provided statements.
Answer
NECT does not fulfill all criteria of an ideal anti-parasitic drug.
The statement 'The nifurtimox and eflornithine combination therapy (NECT) fulfills all the important criteria of an ideal anti-parasitic drug' is false.
Answer for screen readers
The statement 'The nifurtimox and eflornithine combination therapy (NECT) fulfills all the important criteria of an ideal anti-parasitic drug' is false.
More Information
While NECT is a safe and effective treatment for second-stage Trypanosoma brucei gambiense, it is not considered ideal due to potential side effects, the requirement for hospitalization, and specific administration conditions.
Tips
A common mistake is assuming NECT's effectiveness implies it fulfills all ideal drug criteria, such as ease of usage and minimal side effects.
Sources
- Nifurtimox–eflornithine combination therapy - dndi.org
- Human African Trypanosomiasis - FAO Knowledge Repository - openknowledge.fao.org
AI-generated content may contain errors. Please verify critical information
