Which of the following is the most appropriate test to be ordered next? A. Gastroscopy and antral biopsy B. Intrinsic factor antibodies C. Anti-gliadin antibodies D. Colonoscopy
Understand the Problem
The question presents a clinical scenario involving a 46-year-old male with specific symptoms and lab results. It asks which test would be the most appropriate to order next based on the information provided.
Answer
Intrinsic factor antibodies
The final answer is B. Intrinsic factor antibodies
Answer for screen readers
The final answer is B. Intrinsic factor antibodies
More Information
The patient presents with macrocytic anemia (high MCV) and low Vitamin B12, suggesting the possibility of pernicious anemia. Testing for intrinsic factor antibodies would help confirm this diagnosis.
Tips
A common mistake is to overlook the significance of high MCV and low B12, which aligns more with pernicious anemia rather than celiac disease.
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