Which of the following is the biggest limitation of case reports and case series?
Understand the Problem
The question is asking which statement represents the biggest limitation of case reports and case series. It presents multiple choice answers to evaluate the understanding of limitations in these types of studies.
Answer
They cannot establish causation or association.
The biggest limitation of case reports and case series is that they cannot establish causation or association.
Answer for screen readers
The biggest limitation of case reports and case series is that they cannot establish causation or association.
More Information
Case reports and series focus on individual instances and lack the comparative groups needed to establish causation. They are valuable for generating hypotheses but not for confirming them.
Tips
A common mistake is assuming case reports can demonstrate causality when they are primarily descriptive and lack control groups.
Sources
- The clinical case report: a review of its merits and limitations - PMC - pmc.ncbi.nlm.nih.gov
- Case reports and case series - why publish clinical cases - medicioggi.it
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