Which of the following is NOT a characteristic of COX1? A) Readily inducible expression B) Generate prostanoids for 'housekeeping' function C) Constitutively expressed in most cell... Which of the following is NOT a characteristic of COX1? A) Readily inducible expression B) Generate prostanoids for 'housekeeping' function C) Constitutively expressed in most cells D) Involved in the production of prostanoids for maintaining gastric mucosal integrity
Understand the Problem
The question is asking to identify which option does not describe a characteristic of COX1 (Cyclooxygenase-1), a key enzyme involved in the production of prostanoids. To solve it, we need to evaluate each option in terms of COX1's known properties.
Answer
Readily inducible expression.
The final answer is Readily inducible expression.
Answer for screen readers
The final answer is Readily inducible expression.
More Information
COX-1 is considered to be constitutively expressed in most tissues, maintaining cellular homeostasis and producing prostanoids for functions like protecting the gastric mucosa. Unlike COX-2, which is inducible, COX-1 is not typically associated with inducible expression.
Tips
A common mistake is confusing the inducible nature of COX-2 with the constitutive expression of COX-1. Remember that COX-1 is responsible for basic 'housekeeping' functions, unlike COX-2, which is involved in inflammation.
Sources
- Prostaglandins and Inflammation - PMC - PubMed Central - pmc.ncbi.nlm.nih.gov
- Prostanoids in health and disease - PMC - PubMed Central - pmc.ncbi.nlm.nih.gov
- Cyclooxygenase in normal human tissues--is COX-1 really a... - ResearchGate - researchgate.net
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