Which of the following is correctly matched with its role in the Ras activation pathway? A) Raf - MAPK B) Sos - Ras GAP C) Mek - MAPKKK D) Grb2 - Adaptor protein

Understand the Problem

The question is asking to identify which of the provided options is correctly matched with its role in the Ras activation pathway. It involves understanding the relationships between different proteins and their functions within this signaling pathway.

More Information

In the Ras activation pathway, Grb2 functions as an adaptor protein that facilitates the interaction between the activated receptor and the SOS protein, which then aids in the switching of Ras from its GDP-bound form to its active GTP-bound form.

Tips

A common mistake is confusing the roles of MEK and Raf, where people think MEK is the MAPKKK instead of Raf, and confusing adaptor proteins like Grb2 with other signaling molecules.

Sources

• MAPK/ERK pathway - Wikipedia - en.wikipedia.org
• RAS Pathway Drug Discovery - Promega Corporation - promega.com