Which of the following enzyme systems is MAINLY responsible for differences in drug responses in human beings? A. Lipoxygenase enzyme B. Cytochrome P450 enzymes C. Cyclooxygenase e... Which of the following enzyme systems is MAINLY responsible for differences in drug responses in human beings? A. Lipoxygenase enzyme B. Cytochrome P450 enzymes C. Cyclooxygenase enzymes D. Isomerase enzymes E. None. Which of the following routes of drug administration produces 100% bioavailability? A. Oral B. Rectal C. Subcutaneous D. Intravenous E. None.
Understand the Problem
The question is asking about the main enzyme systems involved in drug responses in humans and what routes of drug administration produce 100% bioavailability. It appears to focus on pharmacology and biopharmaceutics.
Answer
Cytochrome P450 enzymes; Intravenous.
The main enzyme system responsible for differences in drug responses in humans is Cytochrome P450 enzymes. The route of drug administration that produces 100% bioavailability is Intravenous.
Answer for screen readers
The main enzyme system responsible for differences in drug responses in humans is Cytochrome P450 enzymes. The route of drug administration that produces 100% bioavailability is Intravenous.
More Information
Cytochrome P450 enzymes are a large family of enzymes playing a pivotal role in drug metabolism, notably affecting individual drug responses. Intravenous administration delivers drugs directly into the bloodstream, ensuring full bioavailability.
Tips
Avoid confusing bioavailability with absorption; intravenous bypasses absorption barriers, ensuring 100% bioavailability.
Sources
- Cytochrome P450 Enzymes and Drug Metabolism in Humans - PMC - pmc.ncbi.nlm.nih.gov
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