Which of the following accurately describes the role of neutrophils and macrophages in the inflammatory response triggered by MSU crystals? A) Macrophages release enzymes that dama... Which of the following accurately describes the role of neutrophils and macrophages in the inflammatory response triggered by MSU crystals? A) Macrophages release enzymes that damage tissue, while neutrophils activate the complement system. B) Macrophages release IL-1β and IL-18, while neutrophils directly attack the crystals. C) Neutrophils phagocytize the crystals, releasing enzymes that perpetuate inflammation, while macrophages contribute to tissue repair. D) Neutrophils release cytokines, while macrophages phagocytize the crystals.
Understand the Problem
The question is asking which statement correctly describes the functions of neutrophils and macrophages in response to MSU (monosodium urate) crystals during inflammation. Each option provides a different perspective on how these immune cells operate within the inflammatory process.
Answer
Neutrophils phagocytize the crystals, releasing enzymes that perpetuate inflammation, while macrophages contribute to tissue repair.
Neutrophils phagocytize the crystals, releasing enzymes that perpetuate inflammation, while macrophages contribute to tissue repair.
Answer for screen readers
Neutrophils phagocytize the crystals, releasing enzymes that perpetuate inflammation, while macrophages contribute to tissue repair.
More Information
Neutrophils and macrophages play a role in the inflammatory response to MSU crystals, which are involved in gout. Neutrophils are known for their ability to ingest and break down these crystals, exacerbating inflammation. Meanwhile, macrophages help in cleaning up the breakdown products and eventually contribute to tissue repair.
Tips
A common mistake is misunderstanding the role of neutrophils as only initiating inflammation; they actively participate throughout the inflammatory process.
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