Which adrenergic receptor has the highest affinity for epinephrine?
Understand the Problem
The question is asking which type of adrenergic receptor has the highest affinity for epinephrine among the given options. This involves understanding the different adrenergic receptors and their interactions with epinephrine.
Answer
Beta-2 adrenergic receptors.
Epinephrine has the highest affinity for beta-2 adrenergic receptors.
Answer for screen readers
Epinephrine has the highest affinity for beta-2 adrenergic receptors.
More Information
Epinephrine interacts with both alpha and beta adrenergic receptors but has a higher affinity for beta-2 receptors. This is why low doses stimulate vasodilation, while high doses have a stronger effect on alpha receptors, causing vasoconstriction.
Tips
A common mistake is confusing receptor affinity with potency. While epinephrine's effects depend on both, it naturally has a higher affinity for beta-2 receptors at lower concentrations.
Sources
- Falsely reported to have higher affinity for Beta-2 receptors than ... - researchgate.net
- Beta Adrenergic Receptor - an overview | ScienceDirect Topics - sciencedirect.com
- Alpha-1 adrenergic receptor - Wikipedia - en.wikipedia.org
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