When studying the effect of various chemicals (e.g. atropine and epinephrine) on the frog heart, the frog heart must be denervated. Why?
Understand the Problem
The question is asking for the reason why the frog heart must be denervated when studying the effects of chemicals like atropine and epinephrine. The options provided present different explanations, and the correct one addresses the necessity to eliminate neural influence on heart rate to accurately assess the chemicals' effects.
Answer
The frog heart is denervated to study drug effects directly on the heart tissue, without neural influence.
The frog heart must be denervated to eliminate the influence of the nervous system, allowing the direct effects of chemicals like atropine and epinephrine on the heart to be studied without interference from neural inputs.
Answer for screen readers
The frog heart must be denervated to eliminate the influence of the nervous system, allowing the direct effects of chemicals like atropine and epinephrine on the heart to be studied without interference from neural inputs.
More Information
Denervation ensures that external neural stimuli do not alter the heart's response to the drugs being studied, providing clearer and more accurate insights into the pharmacodynamics of those drugs.
Tips
It is important to ensure complete denervation; any remaining nerve influence could skew results.
Sources
- Effect of drugs on frog's heart | PPT - SlideShare - slideshare.net
- Frog Heart - sheffbp.co.uk
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