What type of antibody is Mirikizumab classified as?
Understand the Problem
The question is asking to classify Mirikizumab based on its type of antibody. Specifically, it seeks to identify whether it is Human IgG1, Humanized IgG2, Human IgG4, or Human IgM.
Answer
Mirikizumab is a humanized IgG4 monoclonal antibody.
Mirikizumab is classified as a humanized IgG4 monoclonal antibody.
Answer for screen readers
Mirikizumab is classified as a humanized IgG4 monoclonal antibody.
More Information
Mirikizumab is designed to target the p19 subunit of interleukin-23 (IL-23), which is involved in inflammatory processes, making it effective in treating conditions like ulcerative colitis.
Tips
A common mistake might be confusing the specific subclass (IgG4) with other subclasses (e.g. IgG1, IgG2), which have different properties and uses.
Sources
- Mirikizumab - an overview | ScienceDirect Topics - sciencedirect.com
- Mirikizumab as Induction and Maintenance Therapy for Ulcerative ... - nejm.org
- Mirikizumab: Uses, Interactions, Mechanism of Action - DrugBank - go.drugbank.com
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