What triggers the development of the primary ossification center during endochondral ossification?
Understand the Problem
The question is asking what event initiates the development of the primary ossification center during endochondral ossification, a process of bone development.
Answer
Mesenchymal cells differentiating into chondroblasts and osteoblasts triggers the development of the primary ossification center.
The development of the primary ossification center during endochondral ossification is triggered by the differentiation of mesenchymal cells into chondroblasts and hypertrophy of chondrocytes, along with the migration of osteoprogenitor cells that differentiate into osteoblasts.
Answer for screen readers
The development of the primary ossification center during endochondral ossification is triggered by the differentiation of mesenchymal cells into chondroblasts and hypertrophy of chondrocytes, along with the migration of osteoprogenitor cells that differentiate into osteoblasts.
More Information
Endochondral ossification is essential for the formation of long bones, and the primary ossification center is the initial site of bone development within the cartilage model.
Tips
A common mistake is to think that only one factor triggers the ossification center development; it is a combination of cellular and molecular events.
Sources
- Endochondral Ossification - an overview | ScienceDirect Topics - sciencedirect.com
- Endochondral Bone Formation - Basic Science - Orthobullets - orthobullets.com
- Endochondral ossification - Wikipedia - en.wikipedia.org
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