What risk is associated with systemic corticosteroids that is not present with intranasal or ophthalmic corticosteroids?
Understand the Problem
The question is asking about the risks associated with systemic corticosteroids that are distinct from those associated with intranasal or ophthalmic corticosteroids. It requires an understanding of pharmacology and the side effects of different types of corticosteroid administration methods.
Answer
Systemic corticosteroids can affect the hypothalamo-pituitary-adrenal axis, bone density, and growth.
Systemic corticosteroids are associated with an increased risk of affecting the hypothalamo-pituitary-adrenal axis, bone density, and growth, which is not typically a risk with intranasal or ophthalmic corticosteroids.
Answer for screen readers
Systemic corticosteroids are associated with an increased risk of affecting the hypothalamo-pituitary-adrenal axis, bone density, and growth, which is not typically a risk with intranasal or ophthalmic corticosteroids.
More Information
Systemic corticosteroids can cause more widespread effects because they circulate throughout the body as opposed to local corticosteroids which are applied directly to a targeted area, minimizing potential side effects.
Tips
Confusing local with systemic administration can lead to misunderstanding the different side effects and risks correlated with each type of corticosteroid.
Sources
- Systemic Effects of Inhaled Corticosteroids: An Overview - PMC - pmc.ncbi.nlm.nih.gov
- What are Corticosteroids? - HealthyChildren.org - healthychildren.org
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