What physiological process is primarily impaired as a result of beta-cell dysfunction in type 2 diabetes mellitus?
Understand the Problem
The question is asking about the specific physiological process that is affected due to the malfunctioning of beta-cells in type 2 diabetes mellitus. It seeks to identify the correct answer among several options that relate to insulin and glucose metabolism.
Answer
Insulin secretion
The final answer is insulin secretion
Answer for screen readers
The final answer is insulin secretion
More Information
In type 2 diabetes mellitus, beta-cell dysfunction primarily impairs insulin secretion, leading to inadequate regulation of blood glucose levels. This can exacerbate the condition along with insulin resistance, ultimately contributing to hyperglycemia over time.
Tips
A common mistake is to confuse insulin resistance with beta-cell dysfunction. They are distinct processes; beta-cell dysfunction mainly affects insulin secretion.
Sources
- Pancreatic β-cell dysfunction in type 2 diabetes - PubMed Central - pmc.ncbi.nlm.nih.gov
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