What is the primary cause of facial edema in Nephrotic Syndrome?
Understand the Problem
The question is asking about the primary cause of facial edema specifically in the context of Nephrotic Syndrome. The user is looking for a clear understanding of the relationship between Nephrotic Syndrome and facial edema, along with possible contributing factors.
Answer
Protein leakage in urine leads to low blood protein, causing facial edema.
The primary cause of facial edema in Nephrotic Syndrome is the leakage of protein from the blood into the urine, leading to low protein levels in the blood (hypoalbuminemia). This results in fluid moving from the blood vessels into the tissue, causing swelling.
Answer for screen readers
The primary cause of facial edema in Nephrotic Syndrome is the leakage of protein from the blood into the urine, leading to low protein levels in the blood (hypoalbuminemia). This results in fluid moving from the blood vessels into the tissue, causing swelling.
More Information
In Nephrotic Syndrome, the kidneys leak protein into the urine, reducing the protein level in the blood. Lack of proteins like albumin causes a decrease in osmotic pressure, leading to edema as fluid moves into the tissues.
Tips
A common mistake is forgetting that reduced plasma protein levels result in reduced oncotic pressure, which is a key factor in fluid leakage.
Sources
- Nephrotic syndrome - Symptoms & causes - Mayo Clinic - mayoclinic.org
- Nephrotic Syndrome in Adults - NIDDK - niddk.nih.gov
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