What is the lifespan of neutrophils once they enter peripheral circulation?
Understand the Problem
The question is asking about the lifespan of neutrophils in peripheral circulation, which pertains to human biology and the immune system.
Answer
6 to 12 hours, potentially up to 24 hours or longer.
The lifespan of neutrophils once they enter peripheral circulation is generally between 6 to 12 hours. However, some studies suggest it could be up to 24 hours or even longer, possibly 5.4 days.
Answer for screen readers
The lifespan of neutrophils once they enter peripheral circulation is generally between 6 to 12 hours. However, some studies suggest it could be up to 24 hours or even longer, possibly 5.4 days.
More Information
Neutrophils are crucial components of the immune system, acting as first responders to infection. Their short lifespan is key to their function, allowing them to quickly respond and then be cleared to prevent excessive inflammation.
Tips
A common mistake is to assume neutrophils live only for 6-8 hours based on older studies. Recent research suggests a range of durations, including much longer lifespans.
Sources
- PMC Article on Neutrophil Lifespan - pmc.ncbi.nlm.nih.gov
- eClinpath - Neutrophils - eclinpath.com
- Journal of Leukocyte Biology - Neutrophil Half-Life - jlb.onlinelibrary.wiley.com
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