What is the effect of activating AT1 receptors?
Understand the Problem
The question is asking about the physiological effects of activating AT1 receptors, which are a type of receptor involved in the regulation of blood pressure and fluid balance in the body. The user is likely looking for the correct answer among the provided options.
Answer
Activation of AT1 receptors results in vasoconstriction and increased sympathetic activity.
Activation of AT1 receptors leads to vasoconstriction, increased sympathetic nervous activity, sodium and water retention through aldosterone release, and regulation of various downstream signaling pathways.
Answer for screen readers
Activation of AT1 receptors leads to vasoconstriction, increased sympathetic nervous activity, sodium and water retention through aldosterone release, and regulation of various downstream signaling pathways.
More Information
AT1 receptors, when activated by angiotensin II (AngII), influence blood pressure regulation and water balance, crucial in conditions like hypertension and heart failure.
Tips
Confusing the roles of AT1 and AT2 receptors is common. Remember, AT1 is primarily associated with vasoconstriction and other classic effects of the renin-angiotensin system.
Sources
- Angiotensin 1 Receptor - an overview | ScienceDirect Topics - sciencedirect.com
- Intrarenal angiotensin II generation and renal effects of AT1 receptor ... - pubmed.ncbi.nlm.nih.gov
- Angiotensin II signal transduction through the AT1 receptor - portlandpress.com
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