What is the difference between the α and β configurations of a monosaccharide?

Understand the Problem

The question is asking to identify the difference between the alpha and beta configurations of a monosaccharide, specifically focusing on the position of the hydroxyl group.

Answer

In α configuration, the OH on C-1 is opposite C-6. In β, it's on the same side.

The α and β configurations of a monosaccharide differ in the position of the hydroxyl group at the anomeric carbon. In the α configuration, this OH group is on the opposite side of the ring from the CH2OH group (C-6), while in the β configuration, it is on the same side.

Answer for screen readers

The α and β configurations of a monosaccharide differ in the position of the hydroxyl group at the anomeric carbon. In the α configuration, this OH group is on the opposite side of the ring from the CH2OH group (C-6), while in the β configuration, it is on the same side.

More Information

These configurations arise due to the formation of cyclic structures in sugars where the carbon atom forming part of the ring becomes asymmetrical.

Tips

A common mistake is to confuse the positioning relative to the plane of the ring instead of the relative positions to the CH2OH group.

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