What is a significant adverse effect associated with the use of azithromycin in patients with COPD, especially with repeated or prolonged use?
Understand the Problem
The question asks about a significant adverse effect specifically linked to azithromycin use in patients with COPD (Chronic Obstructive Pulmonary Disease), particularly with extended or repeated courses.
Answer
Antimicrobial resistance, cardiovascular toxicity, and hearing impairment.
A significant adverse effect associated with repeated or prolonged use of azithromycin in COPD patients is antimicrobial resistance. Other potential adverse effects include cardiovascular toxicity and hearing impairment.
Answer for screen readers
A significant adverse effect associated with repeated or prolonged use of azithromycin in COPD patients is antimicrobial resistance. Other potential adverse effects include cardiovascular toxicity and hearing impairment.
More Information
Long-term use requires careful consideration of potential risks and benefits for each patient.
Tips
It's important to consider individual patient risk factors and weigh the benefits against potential adverse effects before prescribing long-term azithromycin.
Sources
- Treatment adverse events - thorax.bmj.com
- Azithromycin for the Prevention of COPD Exacerbations - amjmed.com
- Mayo Clinic Q and A: Long-Term Antibiotic Use For Some With COPD - newsnetwork.mayoclinic.org
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