What is a consequence of adipose tissue becoming insulin resistant?
Understand the Problem
The question is asking about the consequences of adipose tissue becoming insulin resistant. It relates to the metabolic effects and how insulin resistance affects lipid metabolism and other tissues in the body.
Answer
Excessive FFA release leads to ectopic fat deposition.
When adipose tissue becomes insulin resistant, it causes the release of excessive free fatty acids (FFA) into the bloodstream, leading to increased synthesis of diacylglycerol (DAG) and triacylglycerol (TAG) in muscle cells and hepatocytes, resulting in ectopic fat deposition.
Answer for screen readers
When adipose tissue becomes insulin resistant, it causes the release of excessive free fatty acids (FFA) into the bloodstream, leading to increased synthesis of diacylglycerol (DAG) and triacylglycerol (TAG) in muscle cells and hepatocytes, resulting in ectopic fat deposition.
More Information
Ectopic fat deposition can disrupt normal metabolic functions in the liver and muscles, contributing to conditions such as non-alcoholic fatty liver disease and insulin resistance in muscles.
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