What distinguishes X-linked severe combined immunodeficiency from other X-linked disorders?
Understand the Problem
The question is asking us to identify the specific features that distinguish X-linked severe combined immunodeficiency (X-SCID) from other X-linked disorders. We need to evaluate the options provided to determine which one correctly highlights a characteristic unique to X-SCID.
Answer
X-SCID is characterized by absent T and NK lymphocytes.
X-linked severe combined immunodeficiency (X-SCID) is distinguished by the absence of T and NK lymphocytes, whereas other immune disorders may have different cellular deficiencies.
Answer for screen readers
X-linked severe combined immunodeficiency (X-SCID) is distinguished by the absence of T and NK lymphocytes, whereas other immune disorders may have different cellular deficiencies.
More Information
X-SCID specifically affects the immune system by severely impacting T and NK cells due to mutations in the γc chain gene, leading to a deficient immune response.
Tips
A common mistake is confusing SCID with other immunodeficiencies that can affect different immune cells or have different underlying genetic causes.
Sources
- X-linked severe combined immunodeficiency - Genetics - MedlinePlus - medlineplus.gov
- Severe combined immunodeficiencies (SCID) - PMC - pmc.ncbi.nlm.nih.gov
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