Two neutropenic patients developed fever not resolved by cefepime. What to add? There were no antifungals. 1. Tazocin 2. Vancomycin
Understand the Problem
The question is asking about the appropriate medication to add for two neupenic patients with fever that did not resolve with cefepime, specifically considering that there were no antifungal treatments administered.
Answer
Add vancomycin.
Add vancomycin. Vancomycin is usually added for febrile neutropenic patients when fever persists despite cefepime therapy.
Answer for screen readers
Add vancomycin. Vancomycin is usually added for febrile neutropenic patients when fever persists despite cefepime therapy.
More Information
When treating febrile neutropenia, vancomycin is often added empirically if the patient's fever persists, as it covers Gram-positive bacteria.
Tips
A common mistake is to add antifungals too early. Antifungal therapy is usually considered after antibacterial adjustments fail to control the fever.
Sources
- How I Treat Febrile Neutropenia - PMC - pmc.ncbi.nlm.nih.gov
- Management of Febrile Neutropenia in Adult Cancer Patients - albertahealthservices.ca
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