The protein that mediates the efflux of cholesterol from cells to HDL is called what?
Understand the Problem
The question is asking to identify the specific protein responsible for transporting cholesterol out of cells and onto high-density lipoprotein (HDL) particles. This is a key process in cholesterol metabolism and reverse cholesterol transport.
Answer
ABCG1
ABCG1 mediates the efflux of cholesterol from cells to HDL particles.
Answer for screen readers
ABCG1 mediates the efflux of cholesterol from cells to HDL particles.
More Information
ABCG1 is expressed in many different cell types. It has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation.
Tips
ABCA1 mediates the efflux of cellular cholesterol to lipid-poor apolipoproteins but not to HDL particles that constitute the bulk of the plasma.
Sources
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