Match the characteristic with the correct immunoglobulin class: found in mucosal linings | IgE, able to cross the placenta | IgM, contains 10 antigen-binding sites | IgG, produced... Match the characteristic with the correct immunoglobulin class: found in mucosal linings | IgE, able to cross the placenta | IgM, contains 10 antigen-binding sites | IgG, produced early in an immune response | IgA.
Understand the Problem
The question is asking to match specific characteristics with the appropriate immunoglobulin classes. This involves identifying the correct immunoglobulin that corresponds to each feature described.
Answer
Mucosal linings: IgA, Cross the placenta: IgG, 10 antigen-binding sites: IgM, Early response: IgM
Found in mucosal linings - IgA, Able to cross the placenta - IgG, Contains 10 antigen-binding sites - IgM, Produced early in an immune response - IgM.
Answer for screen readers
Found in mucosal linings - IgA, Able to cross the placenta - IgG, Contains 10 antigen-binding sites - IgM, Produced early in an immune response - IgM.
More Information
IgA is mainly found in mucosal areas and helps protect these surfaces. IgG is the only immunoglobulin that can cross the placenta, which helps provide immunity to the fetus. IgM, being a pentamer, can bind up to 10 antigens and is produced first in response to an antigen.
Tips
A common mistake is to confuse the early production of IgM with its ability to have multiple antigen-binding sites which is due to its pentameric form.
Sources
- Immune system - IgA, IgG, IgM - Britannica - britannica.com
- Antibody Types: IgM, IgA, IgD, IgG, IgE and Camelid ... - News-Medical - news-medical.net
- Immunoglobulin M - an overview | ScienceDirect Topics - sciencedirect.com
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