In which of the following tissues is GLUT-2 primarily expressed? A) Skeletal muscle B) Liver C) Adipose tissue D) Renal tubules

Understand the Problem

The question is asking for the specific tissue where GLUT-2 is primarily expressed among the given options. To answer this, we need to understand the function and localization of the GLUT-2 transporter in human physiology.

More Information

GLUT2 is a glucose transporter that is highly expressed in tissues such as the liver, intestine, kidney, and pancreatic beta cells. It plays a crucial role in glucose sensing and homeostasis, particularly in the liver, which is a major site for glucose uptake and regulation.

Tips

A common mistake is confusing GLUT2 with other glucose transporters like GLUT4, which is found in muscle and adipose tissues.

Sources

• Glucose Transporter 2 - an overview | ScienceDirect Topics - sciencedirect.com