Explain why Joe is affected with the genetic condition but Elle is not. Use the pedigree analysis diagram provided. You may draw Punnett squares to help you.
Understand the Problem
The question is asking for an explanation of the genetic inheritance that affects Joe but not Elle, using the provided pedigree diagram. The use of Punnett squares for clarification is encouraged.
Answer
Joe is affected (dd); Elle is not because she inherited Dd or DD.
Joe is affected because he inherited two recessive alleles (dd) from carrier parents, resulting in the condition. Elle is not affected because she inherited either one or no recessive alleles, resulting in a Dd or DD genotype.
Answer for screen readers
Joe is affected because he inherited two recessive alleles (dd) from carrier parents, resulting in the condition. Elle is not affected because she inherited either one or no recessive alleles, resulting in a Dd or DD genotype.
More Information
Pedigree charts are valuable for identifying inheritance patterns. In this case, it reveals that Joe's dd genotype is the result of both parents (Ivy and Lee) being carriers.
Tips
A common mistake is not correctly identifying carrier parents. Remember that for a recessive condition, both parents must carry at least one recessive allele.
Sources
- Pedigrees review (article) | Heredity - Khan Academy - khanacademy.org
- 49. Pedigrees and Punnett Squares - openoregon.pressbooks.pub
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