Consider the structures of Tylenol product and the starting material, p-aminophenol. Look up their literature 1H NMR spectra. What changes in the product compared to starting mater... Consider the structures of Tylenol product and the starting material, p-aminophenol. Look up their literature 1H NMR spectra. What changes in the product compared to starting material can help you confirm if your synthesis was successful by analyzing the NMR spectra? Select all that apply.
Understand the Problem
The question is asking about the comparison between the NMR spectra of the product (Tylenol) and the starting material (p-aminophenol) to identify changes that indicate successful synthesis. It requires an understanding of NMR spectroscopy and the structural differences between the two compounds.
Answer
C=O peak, CH3 singlet, one NH2 peak.
The correct selections are: Product spectrum should have a C=O peak, Product spectrum should have a CH3 singlet, Starting material should have two peaks for NH2, while product would only have one.
Answer for screen readers
The correct selections are: Product spectrum should have a C=O peak, Product spectrum should have a CH3 singlet, Starting material should have two peaks for NH2, while product would only have one.
More Information
Tylenol, known as acetaminophen, is synthesized from p-aminophenol mainly by acetylation. The conversion results in the substitution of a hydroxyl group with an acetyl group, resulting in distinct spectral changes in NMR.
Tips
A common mistake is confusing peak intensity (height) with molecular weight, which doesn't directly correlate. Also, forgetting the acetylation changes can lead to missing the CH3 singlet.
Sources
AI-generated content may contain errors. Please verify critical information
