As hosts for over-expressing foreign proteins, bacteria may be preferred over mammalian cells because bacterially over-expressed proteins are: A. Insoluble B. Not post-translationa... As hosts for over-expressing foreign proteins, bacteria may be preferred over mammalian cells because bacterially over-expressed proteins are: A. Insoluble B. Not post-translationally modified C. Not rapidly degraded D. Easy and cheap to produce in large quantities
Understand the Problem
The question is asking about the advantages of using bacteria over mammalian cells for over-expressing foreign proteins. The options provided (A to D) list potential characteristics of bacterially over-expressed proteins.
Answer
Easy and cheap to produce in large quantities.
The final answer is Easy and cheap to produce in large quantities.
Answer for screen readers
The final answer is Easy and cheap to produce in large quantities.
More Information
Bacterial hosts like E. coli are favored for protein expression due to their rapid growth, simplicity, cost-effectiveness, and ability to produce large quantities of protein.
Tips
A common mistake is assuming bacterial hosts are preferred due to protein solubility or modification, but it's mainly due to cost and ease of production.
Sources
- Strategies to Optimize Protein Expression in E. coli - PMC - pmc.ncbi.nlm.nih.gov
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