A patient with a history of asthma is prescribed a beta-blocker for hypertension. Which beta-blocker would be the MOST appropriate choice, considering the patient's respiratory con... A patient with a history of asthma is prescribed a beta-blocker for hypertension. Which beta-blocker would be the MOST appropriate choice, considering the patient's respiratory condition?
Understand the Problem
The question is asking which beta-blocker is most appropriate for a patient with asthma and hypertension. Beta-blockers can exacerbate asthma symptoms, so the choice of beta-blocker is crucial. We need to consider the selectivity of the beta-blockers.
Answer
A cardio-selective beta-blocker like metoprolol or bisoprolol is the most appropriate choice.
The most appropriate beta-blocker for a patient with asthma and hypertension would be a cardio-selective beta-blocker, such as metoprolol or bisoprolol. Non-selective beta-blockers should be avoided.
Answer for screen readers
The most appropriate beta-blocker for a patient with asthma and hypertension would be a cardio-selective beta-blocker, such as metoprolol or bisoprolol. Non-selective beta-blockers should be avoided.
More Information
Cardio-selective beta-blockers primarily target beta-1 receptors, which are mainly located in the heart. This selectivity minimizes the risk of bronchoconstriction, a narrowing of the airways, which can exacerbate asthma symptoms. Non-selective beta-blockers, on the other hand, block both beta-1 and beta-2 receptors. Beta-2 receptors are found in the lungs, and blocking them can lead to bronchoconstriction.
Tips
The key is to choose a beta-blocker that is selective for beta-1 receptors to minimize the impact on the beta-2 receptors in the lungs. Not all beta-blockers are the same; some are non-selective and should be avoided in asthmatic patients.
Sources
- Traditionally, beta-blockers have been contraindicated in asthmatic patients. However, recommendations have aligned for allowing cardio-selective beta-blockers, also known as beta-1 selective, in asthmatics but not non-selective beta-blockers. Non-selective beta-blockers should not be used in patients with asthma. - ncbi.nlm.nih.gov
- Cardioselective beta blockers, e.g. bisoprolol, metoprolol, are less likely to cause bronchoconstriction than non-selective beta blockers, e.g. ... - bpac.org.nz
- Drugs like esmolol, metoprolol, nebivolol, and nadolol may be safer for asthmatic patients, whereas betaxolol, bisoprolol, timolol, and propranolol should be ... - sciencedirect.com
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