A 65-year-old man with diabetes is admitted to the Coronary Care Unit with diagnosis of acute ST elevation anterior myocardial infarction. He developed massive hematemesis followin... A 65-year-old man with diabetes is admitted to the Coronary Care Unit with diagnosis of acute ST elevation anterior myocardial infarction. He developed massive hematemesis following streptokinase infusion. Which of the following drugs would reverse the action of streptokinase? A. Factor VIII concentrate B. Aminocaproic acid C. Protamine D. Vitamin K
Understand the Problem
The question is asking which drug can reverse the effects of streptokinase in a patient who has experienced massive hematemesis following its infusion. This involves an understanding of pharmacology and the specific action of streptokinase.
Answer
Aminocaproic acid
The drug that would reverse the action of streptokinase is aminocaproic acid.
Answer for screen readers
The drug that would reverse the action of streptokinase is aminocaproic acid.
More Information
Aminocaproic acid is used to reverse excessive bleeding caused by fibrinolytic therapy, such as with streptokinase, by inhibiting the conversion of plasminogen to plasmin.
Tips
Common mistakes include confusing protamine with antifibrinolytic agents; protamine is used to reverse the effects of heparin, not streptokinase.
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