A 27-year-old Caucasian female with no previously known medical history presents to her family doctor for evaluation of new skin findings on her back and chest. She notes that thes... A 27-year-old Caucasian female with no previously known medical history presents to her family doctor for evaluation of new skin findings on her back and chest. She notes that these lesions are slightly raised and highly pruritic (itchy), and that they began this morning when she put on her shirt. She was concerned about the possibility of bug bites initially, but she noted that 4 days ago, she had tried to switch to a more floral detergent for her clothes. Given this history, which of the following is most likely present in terms of pathophysiologic manifestations?
Understand the Problem
The question is asking for the pathophysiologic manifestations related to the described symptoms in a patient with a history of new itchy lesions. The focus is on identifying the most likely underlying immunological response based on the symptoms and recent exposure to a potential allergen, a floral detergent.
Answer
Type I Hypersensitivity based response by hyper-proliferation of IgE-secreting B cells.
The final answer is a Type I Hypersensitivity response characterized by hyper-proliferation of IgE-secreting B cells.
Answer for screen readers
The final answer is a Type I Hypersensitivity response characterized by hyper-proliferation of IgE-secreting B cells.
More Information
The use of a new floral detergent suggests an allergic reaction, typical of a Type I hypersensitivity response, which involves IgE antibodies and leads to symptoms like itching and rash.
Tips
A common mistake is confusing Type I and Type IV hypersensitivity reactions. Remember, Type I involves IgE and immediate responses.
Sources
- Dermatitis - Symptoms and causes - Mayo Clinic - mayoclinic.org
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