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Questions and Answers
What is the primary function of the blood-nerve barrier?
What is the primary function of the blood-nerve barrier?
- To innervate the spinal cord
- To allow the passage of molecules
- To maintain the fiber's environment (correct)
- To classify nerve fibers
What type of nerve fiber innervates the brain?
What type of nerve fiber innervates the brain?
- Cranial nerve (correct)
- Spinal nerve
- Collateral ganglion
- Terminal ganglion
What is the main component of the peripheral nervous system?
What is the main component of the peripheral nervous system?
- Central nervous system
- Nerves (correct)
- Ganglia
- Axons
What is the purpose of the endoneurium?
What is the purpose of the endoneurium?
What type of ganglion is composed of cell bodies of nerve fibers?
What type of ganglion is composed of cell bodies of nerve fibers?
What is the function of the perineurium?
What is the function of the perineurium?
What is the classification of a nerve fiber that innervates the spinal cord?
What is the classification of a nerve fiber that innervates the spinal cord?
What is found in the endoneurium besides axons?
What is found in the endoneurium besides axons?
What is the primary factor that determines the flow of blood in capillaries?
What is the primary factor that determines the flow of blood in capillaries?
What is the function of sweat glands during stressful situations?
What is the function of sweat glands during stressful situations?
What is the effect of sympathetic stimulation on salivary glands?
What is the effect of sympathetic stimulation on salivary glands?
What is the relationship between the sympathetic and parasympathetic nervous systems in salivary glands?
What is the relationship between the sympathetic and parasympathetic nervous systems in salivary glands?
Which of the following nervous systems is responsible for the 'fight or flight' response?
Which of the following nervous systems is responsible for the 'fight or flight' response?
What is the effect of parasympathetic stimulation on salivary glands?
What is the effect of parasympathetic stimulation on salivary glands?
What is the primary function of the sympathetic nervous system in arterioles?
What is the primary function of the sympathetic nervous system in arterioles?
What is the relationship between the sympathetic and parasympathetic nervous systems in terms of their functions?
What is the relationship between the sympathetic and parasympathetic nervous systems in terms of their functions?
What is the name of the division of the efferent nervous system that receives no mention in the classification of the nervous system into somatic and autonomic nervous systems?
What is the name of the division of the efferent nervous system that receives no mention in the classification of the nervous system into somatic and autonomic nervous systems?
What type of stimuli can afferent neurons receive?
What type of stimuli can afferent neurons receive?
What is the primary function of the sympathetic nervous system in emergency situations?
What is the primary function of the sympathetic nervous system in emergency situations?
Which type of glands are innervated by only the sympathetic nervous system?
Which type of glands are innervated by only the sympathetic nervous system?
What is the characteristic of the dual innervation of organs by both sympathetic and parasympathetic fibers?
What is the characteristic of the dual innervation of organs by both sympathetic and parasympathetic fibers?
What is the location of the enteric nervous system?
What is the location of the enteric nervous system?
What is the direction of travel of afferent fibers compared to efferent fibers?
What is the direction of travel of afferent fibers compared to efferent fibers?
What is the general effect of the parasympathetic nervous system on the body's activity?
What is the general effect of the parasympathetic nervous system on the body's activity?
What type of receptors are activated by nicotine and can be found on postganglionic cell bodies of all autonomic ganglia?
What type of receptors are activated by nicotine and can be found on postganglionic cell bodies of all autonomic ganglia?
What is the result of IP3 binding to a receptor in the sarcoplasmic reticulum?
What is the result of IP3 binding to a receptor in the sarcoplasmic reticulum?
What is the effect of NE binding to an alpha receptor?
What is the effect of NE binding to an alpha receptor?
What is the function of muscarinic receptors in the heart?
What is the function of muscarinic receptors in the heart?
What is the effect of ACh on the heart when it binds to a muscarinic receptor?
What is the effect of ACh on the heart when it binds to a muscarinic receptor?
What is the mechanism of action of Metoprolol?
What is the mechanism of action of Metoprolol?
What is the effect of Salbutamol on the bronchioles?
What is the effect of Salbutamol on the bronchioles?
What is the primary mechanism involved in the activation of β1 adrenergic receptor?
What is the primary mechanism involved in the activation of β1 adrenergic receptor?
What is the effect of phosphorylation of sarcoplasmic reticulum receptors in the heart?
What is the effect of phosphorylation of sarcoplasmic reticulum receptors in the heart?
Which region of the CNS is NOT involved in the control of skeletal muscle activity?
Which region of the CNS is NOT involved in the control of skeletal muscle activity?
What is the effect of Ca2+ ion binding to troponin in the heart?
What is the effect of Ca2+ ion binding to troponin in the heart?
What is the primary neurotransmitter released by motor neurons at the neuromuscular junction?
What is the primary neurotransmitter released by motor neurons at the neuromuscular junction?
What is the effect of activation of protein kinase in the heart?
What is the effect of activation of protein kinase in the heart?
What is the characteristic of the motor end plate at the neuromuscular junction?
What is the characteristic of the motor end plate at the neuromuscular junction?
What is the term for the progressive degeneration of motor neurons, as seen in Lou Gehrig's disease?
What is the term for the progressive degeneration of motor neurons, as seen in Lou Gehrig's disease?
What is the purpose of the perineurium in the peripheral nervous system?
What is the purpose of the perineurium in the peripheral nervous system?
What is the classification of a nerve fiber that comes from the brain?
What is the classification of a nerve fiber that comes from the brain?
What is the function of the endoneurium in the peripheral nervous system?
What is the function of the endoneurium in the peripheral nervous system?
What is the term for the bundles of axons in the peripheral nervous system?
What is the term for the bundles of axons in the peripheral nervous system?
What is the term for the cell bodies of neurons outside the central nervous system?
What is the term for the cell bodies of neurons outside the central nervous system?
What is the purpose of the reticular fibers in the endoneurium?
What is the purpose of the reticular fibers in the endoneurium?
What is the type of connective tissue found in the outermost covering of a nerve?
What is the type of connective tissue found in the outermost covering of a nerve?
What is the term for the blood vessels found in the epineurium?
What is the term for the blood vessels found in the epineurium?
What is the function of mast cells and macrophages in the nervous system?
What is the function of mast cells and macrophages in the nervous system?
What is the characteristic of the superficial region of the epineurium compared to the deeper region?
What is the characteristic of the superficial region of the epineurium compared to the deeper region?
What is the location of capillaries in a nerve?
What is the location of capillaries in a nerve?
What is the shape of arteries compared to veins in the epineurium?
What is the shape of arteries compared to veins in the epineurium?
Which type of neuron is responsible for integrating afferent information and formulating an efferent response?
Which type of neuron is responsible for integrating afferent information and formulating an efferent response?
What is the direction of travel of the signal in an afferent fiber?
What is the direction of travel of the signal in an afferent fiber?
What is the site of release of neurotransmitters in an efferent neuron?
What is the site of release of neurotransmitters in an efferent neuron?
Which part of the neuron receives the signal from the afferent neuron?
Which part of the neuron receives the signal from the afferent neuron?
What is the function of the axon terminal of the efferent neuron?
What is the function of the axon terminal of the efferent neuron?
What is the site of integration of afferent information?
What is the site of integration of afferent information?
What is the primary characteristic of the cell bodies in sensory ganglia?
What is the primary characteristic of the cell bodies in sensory ganglia?
What is the function of the satellite glial cells in ganglia?
What is the function of the satellite glial cells in ganglia?
What is the characteristic of lipofuscin in ganglia?
What is the characteristic of lipofuscin in ganglia?
What is the difference between sensory ganglia and autonomic ganglia?
What is the difference between sensory ganglia and autonomic ganglia?
What is the characteristic of the efferent nerve pathways in the autonomic nervous system?
What is the characteristic of the efferent nerve pathways in the autonomic nervous system?
What is the type of neuron found in autonomic ganglia?
What is the type of neuron found in autonomic ganglia?
What is the primary function of the adrenal cortex?
What is the primary function of the adrenal cortex?
What is the effect of alpha 1 receptors on arterioles?
What is the effect of alpha 1 receptors on arterioles?
What is the primary messenger system used by beta 1 receptors?
What is the primary messenger system used by beta 1 receptors?
Which type of receptors have a greater sensitivity towards norepinephrine?
Which type of receptors have a greater sensitivity towards norepinephrine?
What is the effect of beta 2 receptors on bronchioles?
What is the effect of beta 2 receptors on bronchioles?
Which type of receptors are inhibitory, and found mainly in the smooth muscles of the digestive tract?
Which type of receptors are inhibitory, and found mainly in the smooth muscles of the digestive tract?
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Study Notes
Organization of the Vertebrate Nervous System
- The Peripheral Nervous System (PNS) surrounds bundles of axons (fascicles)
- The PNS has two divisions: Afferent Nervous System and Efferent Nervous System
Afferent Nervous System
- Receives and transmits sensory information from the periphery to the Central Nervous System (CNS)
- Consists of afferent neurons that inform the CNS about conditions in the external and internal environment
- Can receive either sensory (outside) or visceral (inside) stimuli
Efferent Nervous System
- Transmits motor signals from the CNS to effector organs (muscles and glands)
- Consists of efferent neurons that carry instructions from the CNS to effector organs
- Divided into Somatic Nervous System and Autonomic Nervous System
Somatic Nervous System
- Innervates skeletal muscles (voluntary control)
- Consists of motor neurons that release neurotransmitter ACh, stimulating muscle contraction
- Includes motor neurons that originate in the spinal cord or brain stem and end on skeletal muscles
Autonomic Nervous System (ANS)
- Innervates smooth muscles, cardiac muscles, and glands (involuntary control)
- Divided into Sympathetic Nervous System (SNS) and Parasympathetic Nervous System (PNS)
- SNS dominates in emergency or stressful situations, promoting responses that prepare the body for strenuous physical activity
- PNS has a more general function, promoting rest and digestion
Neuron Classification
- Afferent neurons: inform CNS about conditions in the external and internal environment
- Efferent neurons: carry instructions from CNS to effector organs
- Interneurons: found entirely within CNS, integrating afferent information and formulating an efferent response
Receptors and Neurotransmitters
- Adrenergic Receptors (α and β): respond to Norepinephrine (NE) and Epinephrine (E)
- Cholinergic Receptors (nicotinic and muscarinic): respond to Acetylcholine (ACh)
- α receptors: cause muscle contraction and vasoconstriction
- β receptors: cause muscle relaxation and vasodilation
- NE and E bind to α and β receptors, with differing affinities
- β1 receptors: found in the heart, respond to NE and E
- β2 receptors: found in the bronchioles, respond to E
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