Normal vascular Growth Quiz

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What is the process called when vascularity increases in a tissue due to increased metabolism?

Angiogenesis

In which type of tissue does angiogenesis occur more slowly?

Old, well-established tissues

What is the time required for long-term regulation of angiogenesis?

Both options

What is the final degree of response to angiogenesis like in younger tissues compared to older tissues?

<p>Better in younger tissues</p> Signup and view all the answers

What is one example of increased vascularity in tissues due to low atmospheric oxygen?

<p>Increased vascularity in animals at high altitudes</p> Signup and view all the answers

What effect does excess oxygen have on vascular growth in premature babies?

<p>Cessation of new vascular growth</p> Signup and view all the answers

Which of the following factors is NOT involved in the formation of new blood vessels?

<p>Angiogenin</p> Signup and view all the answers

What is the condition called when retinal vessels grow out from the retina into the eye's vitreous humor, eventually causing blindness?

<p>Retrolental fibroplasia</p> Signup and view all the answers

What is the first step in angiogenesis?

<p>Dissolution of the basement membrane of the endothelial cells</p> Signup and view all the answers

What is the goal of tissue repair?

<p>To restore normal function with native parenchymal and connective tissue</p> Signup and view all the answers

Which cells contribute to the restoration of damaged tissues during tissue repair?

<p>All of the above</p> Signup and view all the answers

What is the process of new blood vessel development from existing vessels called?

<p>Angiogenesis</p> Signup and view all the answers

What is the final step in angiogenesis?

<p>Recruitment of periendothelial cells</p> Signup and view all the answers

Which of the following is a key factor in the process of angiogenesis?

<p>Formation of the vascular lumen</p> Signup and view all the answers

What role do fibroblast growth factors (FGFs) play in angiogenesis?

<p>Stimulate the proliferation of endothelial cells</p> Signup and view all the answers

What are angiopoietins 1 and 2 (Ang 1 and Ang 2) responsible for in angiogenesis?

<p>Playing a role in angiogenesis and vascular maturation</p> Signup and view all the answers

What is the role of vascular endothelial growth factors (VEGFs) in angiogenesis?

<p>Stimulate migration and proliferation of endothelial cells</p> Signup and view all the answers

What is the main reason why solid tumors need to induce angiogenesis?

<p>To ensure the supply of oxygen and nutrients</p> Signup and view all the answers

What are the sources of pro-angiogenic factors in angiogenesis?

<p>All of the above</p> Signup and view all the answers

What alters the production of pro-angiogenic factors in angiogenesis?

<p>All of the above</p> Signup and view all the answers

Which of the following is a characteristic of controlled neovascularization?

<p>Formation of new blood vessels in wound healing</p> Signup and view all the answers

What happens when oxygen levels are low in a cell?

<p>HIF binds to EPO and other genes</p> Signup and view all the answers

Which molecule is a potent inhibitor of endothelial cell proliferation and migration?

<p>Endostatin</p> Signup and view all the answers

Which disease is characterized by tumors in multiple organs, including the brain, spinal cord, eyes, and kidneys?

<p>Von Hippel-Lindau disease</p> Signup and view all the answers

What is the clinical significance of coronary collaterals in myocardial infarction?

<p>They have no clinical relevance</p> Signup and view all the answers

Do new blood vessels form in the heart after a myocardial infarction?

<p>Yes, through granulation scar formation</p> Signup and view all the answers

What is the role of capillary density in myocardial infarction?

<p>It is not affected by myocardial infarction</p> Signup and view all the answers

Which process is NOT associated with controlled neovascularization?

<p>Retinopathy</p> Signup and view all the answers

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