Angiogenesis and Neovessel Formation
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Questions and Answers

Vasculogenesis is driven by local ECs.

False

Diabetic foot ulcer is a result of enhanced angiogenesis.

False

VEGF-A stimulates lymphangiogenesis.

True

Endothelial cells are responsible for reestablishing vascular support in response to stimuli such as a wound.

<p>True</p> Signup and view all the answers

Critical limb ischemia occurs when blood flow to limbs is increased.

<p>False</p> Signup and view all the answers

Endothelial cells make up the entirety of the blood vessel wall in all types of blood vessels.

<p>False</p> Signup and view all the answers

Nitric oxide is produced by Vascular Smooth Muscle Cells (VSMCs).

<p>False</p> Signup and view all the answers

Endothelial cells are omnipotent: they have the same structure and functional properties regardless of the organ or tissue they are found in.

<p>False</p> Signup and view all the answers

Endothelial cells only allow essential nutrients and oxygen to pass through their selectively permeable barrier.

<p>False</p> Signup and view all the answers

Endothelial cells can proliferate and migrate to form new blood vessels in response to tissue injury or increased oxygen and nutrient demand.

<p>True</p> Signup and view all the answers

Myosin light chain dephosphorylation is achieved through calcium pumping back into SR by SERCA and calcium extrusion out of the cell by PMCA and NCX.

<p>True</p> Signup and view all the answers

Reducing MLCK activity is a mechanism for myosin light chain dephosphorylation.

<p>False</p> Signup and view all the answers

Rho/ROCK Signaling is involved in the pathogenesis of Atherosclerosis.

<p>True</p> Signup and view all the answers

Vascular Endothelial Cells form a multi-cellular layer lining the lumen of all blood vessels.

<p>False</p> Signup and view all the answers

Endothelial Cells account for about 5 kg of an adult human body.

<p>False</p> Signup and view all the answers

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