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Questions and Answers
Vasculogenesis is driven by local ECs.
False
Diabetic foot ulcer is a result of enhanced angiogenesis.
False
VEGF-A stimulates lymphangiogenesis.
True
Endothelial cells are responsible for reestablishing vascular support in response to stimuli such as a wound.
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Critical limb ischemia occurs when blood flow to limbs is increased.
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Endothelial cells make up the entirety of the blood vessel wall in all types of blood vessels.
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Nitric oxide is produced by Vascular Smooth Muscle Cells (VSMCs).
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Endothelial cells are omnipotent: they have the same structure and functional properties regardless of the organ or tissue they are found in.
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Endothelial cells only allow essential nutrients and oxygen to pass through their selectively permeable barrier.
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Endothelial cells can proliferate and migrate to form new blood vessels in response to tissue injury or increased oxygen and nutrient demand.
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Myosin light chain dephosphorylation is achieved through calcium pumping back into SR by SERCA and calcium extrusion out of the cell by PMCA and NCX.
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Reducing MLCK activity is a mechanism for myosin light chain dephosphorylation.
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Rho/ROCK Signaling is involved in the pathogenesis of Atherosclerosis.
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Vascular Endothelial Cells form a multi-cellular layer lining the lumen of all blood vessels.
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Endothelial Cells account for about 5 kg of an adult human body.
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