Renal pylonephritis
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Questions and Answers

Which organ is most commonly involved in amyloidosis?

  • Lungs
  • Kidney (correct)
  • Liver
  • Heart

What is the main component of amyloid deposits in the glomerulus?

  • Hyaline
  • Amyloid A (correct)
  • Fibrin
  • Collagen

Which location of amyloid deposition predominates in cats and Shar-Pei dogs?

  • Glomerular
  • Cortical
  • Medullary (correct)
  • Interstitial

Which breeds are predisposed to amyloidosis?

<p>Shar-Pei dogs (D)</p> Signup and view all the answers

What is the most common form of amyloidosis?

<p>Reactive systemic amyloidosis (B)</p> Signup and view all the answers

What are the clinical manifestations of amyloidosis in the kidneys?

<p>Chronic renal insufficiency and proteinuria (B)</p> Signup and view all the answers

What causes the glomerular filtration barrier to be damaged in nephrotic syndrome?

<p>Inflammation in the kidneys (B)</p> Signup and view all the answers

What can be seen histologically in amyloidosis?

<p>Extracellular deposition of pale haemogenous proteinaceous material (B)</p> Signup and view all the answers

What stain is used to visualize amyloid deposits in histology?

<p>Congo red (B)</p> Signup and view all the answers

What is one of the other causes of nephrotic syndrome, aside from amyloidosis?

<p>Glomerulonephritis (C)</p> Signup and view all the answers

Which of the following is a common clinical sign of nephrotic syndrome?

<p>Hyperlipidemia (D)</p> Signup and view all the answers

What is the main cause of proteinuria in glomerulonephritis?

<p>Deposition of immune complexes (C)</p> Signup and view all the answers

Which of the following does NOT lead to protein-losing nephropathy or nephrotic syndrome?

<p>Tubular disease (B)</p> Signup and view all the answers

What is the main cause of acute tubular necrosis?

<p>Hypoxia/ischemia (C)</p> Signup and view all the answers

Which of the following is a common consequence of acute tubular necrosis?

<p>Acute renal failure (B)</p> Signup and view all the answers

What is the main cause of suppurative interstitial nephritis?

<p>Bacterial emboli (A)</p> Signup and view all the answers

Which of the following is a common cause of chronic interstitial nephritis?

<p>Chronic glomerulonephritis (D)</p> Signup and view all the answers

Which of the following is a common consequence of chronic interstitial nephritis?

<p>Chronic renal failure (A)</p> Signup and view all the answers

What is the characteristic histological appearance of amyloid deposits in the kidneys?

<p>Extracellular deposition of eosinophilic, homogeneous and proteinaceous material</p> Signup and view all the answers

What is the most common cause of reactive systemic amyloidosis?

<p>Chronic antigen stimulation</p> Signup and view all the answers

What clinical manifestations are commonly seen in amyloidosis of the kidneys?

<p>Chronic renal insufficiency and proteinuria (nephrotic syndrome)</p> Signup and view all the answers

What is the function of the glomerulus?

<p>To filter out large proteins</p> Signup and view all the answers

What can happen when amyloidosis affects the glomerulus?

<p>It can lead to nephrotic syndrome</p> Signup and view all the answers

What is the underlying cause of amyloidosis?

<p>Chronic inflammation</p> Signup and view all the answers

What breeds are predisposed to amyloidosis?

<p>Shar-Pei dogs, Abyssinian and Siamese cats</p> Signup and view all the answers

What is the main component of amyloid deposits in the glomerulus?

<p>Amyloid A</p> Signup and view all the answers

What is the most common form of amyloidosis?

<p>Reactive systemic amyloidosis (AA amyloid)</p> Signup and view all the answers

What is one of the other causes of nephrotic syndrome, aside from amyloidosis?

<p>Glomerulonephritis</p> Signup and view all the answers

What are the clinical signs of nephrotic syndrome?

<p>generalised oedema, ascites, pleural effusion, hyperlipidaemia</p> Signup and view all the answers

What are the common causes of glomerulonephritis?

<p>deposition of immune complexes, persistent antigenemia, viral infections, chronic bacterial infections, chronic parasitism, neoplasia</p> Signup and view all the answers

What is the consequence of chronic glomerulonephritis?

<p>glomerulosclerosis</p> Signup and view all the answers

What are the common causes of acute tubular necrosis?

<p>hypoxia/ischaemia, nephrotoxicity</p> Signup and view all the answers

What is the consequence of acute tubular necrosis?

<p>acute renal failure or chronic interstitial nephritis</p> Signup and view all the answers

What are the main types of tubulointerstitial nephritis?

<p>suppurative, non-suppurative</p> Signup and view all the answers

What is the consequence of chronic interstitial nephritis?

<p>chronic renal failure</p> Signup and view all the answers

What are the clinical signs of amyloidosis in the kidneys?

<p>proteinuria, renal failure</p> Signup and view all the answers

What is the main cause of suppurative interstitial nephritis?

<p>bacterial emboli</p> Signup and view all the answers

What is the main cause of proteinuria in glomerulonephritis?

<p>damaged glomerular filtration barrier</p> Signup and view all the answers

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