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Xeroderma Pigmentosum: Mutations and DNA Repair

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Xeroderma Pigmentosum: Mutations and DNA Repair

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Questions and Answers

What is the purpose of replica plating in mutation detection?

To screen for mutant strains of a colony-forming microorganism (correct)

To isolate microorganisms with resistance to viruses

To detect targeted mutations using PCR

To identify conditional mutations

What is a common conditional mutation used in mutation detection?

Chemical resistance

Heat sensitivity (correct)

Cold sensitivity

Heat resistance

What is the purpose of incubating at different temperatures in conditional mutation detection?

To screen for conditional mutations (correct)

To identify resistant cells

To isolate microorganisms with heat resistance

To detect targeted mutations

How are microorganisms like E. coli and yeast screened for resistance to viruses?

By screening for growth when wild-type cells will not Signup and view all the answers

What is the purpose of molecular screens in mutation detection?

To detect targeted mutations Signup and view all the answers

What techniques are used in molecular screens for mutation detection?

PCR, restriction enzyme analysis and DNA probing Signup and view all the answers

What is the advantage of using microorganisms like E. coli and yeast in mutation detection?

They are easily screened for resistance to viruses, chemicals or drugs Signup and view all the answers

What is the purpose of isolating conditional mutations in mutation detection?

To study genes that are usually lethal Signup and view all the answers

What is the advantage of using conditional mutations in mutation detection?

They allow for the study of genes that are usually lethal Signup and view all the answers

What is the purpose of screening for mutant strains of a colony-forming microorganism?

To select for further study Signup and view all the answers