Podcast
Questions and Answers
What is the main reason behind the lack of B-cells in X-linked agammaglobulinemia (Bruton’s)?
What is the main reason behind the lack of B-cells in X-linked agammaglobulinemia (Bruton’s)?
- Deficiency in the production of antibodies
- Excessive production of light chains inhibiting B-cell development
- Overproduction of T-cells leading to suppression of B-cells
- Inability of pro-B cells to differentiate into pre-B cells due to tyrosine kinase deficiency (correct)
Which condition is characterized by hypogammaglobulinemia, reduced lymphocytes, and decreased T-cell activity?
Which condition is characterized by hypogammaglobulinemia, reduced lymphocytes, and decreased T-cell activity?
- Common variable immunodeficiency (correct)
- Isolated IgA deficiency
- X-linked agammaglobulinemia (Bruton’s)
- Hypogammaglobulinemia
What is a common symptom associated with Isolated IgA deficiency?
What is a common symptom associated with Isolated IgA deficiency?
- Otitis media (correct)
- Arthritis
- Kidney failure
- Heart disease
Why can a celiac test result show a false negative in a patient with IgA deficiency?
Why can a celiac test result show a false negative in a patient with IgA deficiency?
What is the primary biological defect in Hyper IgM syndrome?
What is the primary biological defect in Hyper IgM syndrome?
Which immune deficiency can result in life-threatening anaphylaxis post blood transfusion due to recognition of transfused IgA as foreign?
Which immune deficiency can result in life-threatening anaphylaxis post blood transfusion due to recognition of transfused IgA as foreign?
Which of the following is true about hyper IgM syndrome?
Which of the following is true about hyper IgM syndrome?
What is the prognosis for hyper IgM syndrome?
What is the prognosis for hyper IgM syndrome?
DiGeorge syndrome is also known as:
DiGeorge syndrome is also known as:
What is the primary biological cause of DiGeorge syndrome?
What is the primary biological cause of DiGeorge syndrome?
What is the primary immunodeficiency associated with severe combined immunodeficiency (SCID)?
What is the primary immunodeficiency associated with severe combined immunodeficiency (SCID)?
Which of the following is an example of an innate immunodeficiency?
Which of the following is an example of an innate immunodeficiency?
