INORG CHEM
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Questions and Answers

A patient with peptic ulcer disease (PUD) requires a medication to protect the mucosal lining of the stomach. Which of the following substances, based on its pharmacologic use, would be most appropriate?

  • Titanium Oxide
  • Selenium Sulfide
  • Tantalum
  • Bismuth (correct)

In the formulation of a new sunscreen product, a manufacturer needs an ingredient that will effectively block solar rays and is safe for topical application. Which of the following would be the MOST suitable choice?

  • Bismuth
  • EDTA
  • Titanium Oxide (correct)
  • Selenium

A patient is prescribed 'Selsun Blue' for a skin condition. What is the MOST likely condition being treated?

  • Psoriasis
  • Dandruff (correct)
  • Acne
  • Eczema

In a scenario requiring a biocompatible material for surgical bone repair that won't adversely affect surrounding tissues, which of the following materials would be MOST suitable?

<p>Tantalum (B)</p> Signup and view all the answers

An athlete is looking to improve recovery and reduce oxidative stress. Which of the official gasses, when combined synergistically with an appropriate trace element, could improve these outcomes?

<p>Combining Oxygen with Selenium (C)</p> Signup and view all the answers

A patient presents with rheumatoid arthritis and is prescribed a gold compound. Which of the following best describes a potential side effect and the most probable brand name of the medication causing it?

<p>Glossitis from Auranofin (A)</p> Signup and view all the answers

A researcher is studying the antimicrobial properties of various metals. Which characteristic of silver makes it effective at inhibiting microorganisms even at low concentrations?

<p>Oligodynamic action (D)</p> Signup and view all the answers

A patient is diagnosed with argyria. Which of the following substances is most likely the cause of this condition?

<p>Silver (A)</p> Signup and view all the answers

Which of the following is the correct ratio of nitric acid to hydrochloric acid in Aqua Regia, a solution capable of dissolving gold?

<p>1 HNO3 : 3 HCl (A)</p> Signup and view all the answers

A farmer is preparing a solution to prevent fungal growth on crops and requires copper sulfate. Which of the following common names would most likely be used to refer to this compound?

<p>Blue vitriol (B)</p> Signup and view all the answers

Which of the following silver proteinates is correctly matched with its silver content percentage?

<p>Arygol: 19-25% (D)</p> Signup and view all the answers

A patient presents with symptoms of mercury toxicity. According to the information, which of the following would be the MOST appropriate initial treatment?

<p>Administer Sodium formalde sulfoxylate. (A)</p> Signup and view all the answers

In a laboratory setting, a researcher needs to induce vomiting in a patient who has ingested phosphorous. Which treatment is most appropriate?

<p>Administering copper sulfate (B)</p> Signup and view all the answers

Magnesium oxide is a component of the universal antidote. What are the OTHER ingredients?

<p>Activated charcoal and Tannic acid (B)</p> Signup and view all the answers

A researcher is formulating a gastric antacid. Which of the following magnesium compounds would be most suitable for this application?

<p>An insoluble magnesium compound (D)</p> Signup and view all the answers

A patient is experiencing copper toxicity. Which of the following medications is the recommended treatment to counteract this form of poisoning?

<p>Penicillamine (B)</p> Signup and view all the answers

A patient is suffering from barium toxicity. Which of the following medications would be MOST appropriate to administer?

<p>Magnesium Sulfate (C)</p> Signup and view all the answers

A patient exhibits symptoms consistent with 'boiled lobster appearance.' Which of the following toxicities is MOST likely the cause?

<p>Boron (B)</p> Signup and view all the answers

Which of the following statements correctly describes the relationship between calcium and Vitamin D?

<p>Vitamin D is needed for the absorption of calcium. (D)</p> Signup and view all the answers

A patient is experiencing muscle spasms and is diagnosed with hypomagnesemia. Which form of magnesium is MOST likely to be administered intravenously to address this condition?

<p>Epsom salt (A)</p> Signup and view all the answers

In a formulation containing 'Ladd's paste,' which of the following elements is present?

<p>Aluminum (D)</p> Signup and view all the answers

Which of the following is a characteristic effect of chronic cadmium toxicity, specifically associated with 'Itai-Itai' disease?

<p>Severe bone pain and skeletal deformities (C)</p> Signup and view all the answers

What is the primary mechanism by which carbon dioxide ($CO_2$) causes death?

<p>Displacement of oxygen leading to asphyxia (A)</p> Signup and view all the answers

A patient presents with symptoms of silicosis. Based on the provided information, what is the recommended treatment approach?

<p>Inhalation of Aluminum oxide ($Al_2O_3$) dust (A)</p> Signup and view all the answers

Stannous fluoride ($SnF_2$) is used as an anticariogenic agent. What property of stannous fluoride requires that its solutions be freshly prepared?

<p>Ease of oxidation (A)</p> Signup and view all the answers

A child ingests a significant amount of lead. Which of the following would be the MOST appropriate initial treatment?

<p>Focus on chelation therapy after initial stabilization (A)</p> Signup and view all the answers

What is the role of Calcium Sulfate ($CaSO_4$) in the manufacturing of dental materials?

<p>Diluent (D)</p> Signup and view all the answers

Insulin relies on the presence of which metal for its proper function?

<p>Zinc (C)</p> Signup and view all the answers

Alum is used in the treatment of silicosis. What is being referred to when the content mentions 'Alum'?

<p>Aluminum (D)</p> Signup and view all the answers

A patient is experiencing metal fume fever. Based on the content, what is the most appropriate antidote to administer?

<p>Sodium Bicarbonate (B)</p> Signup and view all the answers

What is the significance of nitrogen being referred to as 'azote'?

<p>It means 'without life', reflecting its inert nature (A)</p> Signup and view all the answers

Which of the following solutions is commonly used as an electrolyte replenisher?

<p>Ringer's Solution (A)</p> Signup and view all the answers

What is the primary use of Sodium Bicarbonate, as listed in the options below?

<p>Antacid (B)</p> Signup and view all the answers

Which of the following is a synonym for Sodium Hydroxide?

<p>Caustic Soda (A)</p> Signup and view all the answers

What property makes Sodium Thiosulfate useful in treating cyanide poisoning?

<p>Serving as an antidote (B)</p> Signup and view all the answers

Which of the following is a use for Potassium Permanganate?

<p>Volumetric solution in Permanganometry (D)</p> Signup and view all the answers

What is the common name for Potassium Bitartrate?

<p>Cream of Tartar (D)</p> Signup and view all the answers

What is a key application of Ammonium Chloride in analytical chemistry?

<p>A buffer in zinc analysis (C)</p> Signup and view all the answers

What is the approximate percentage of ammonia in Strong Ammonia Solution?

<p>27-31% (C)</p> Signup and view all the answers

What distinguishes copper from most other metals?

<p>Its reddish color (B)</p> Signup and view all the answers

What is the role of copper in the human body?

<p>Enhances the absorption of iron (C)</p> Signup and view all the answers

In which of the following alloys is tin (Sn) a component?

<p>Bronze (B)</p> Signup and view all the answers

What condition is associated with copper overload in the body?

<p>Wilson's disease (A)</p> Signup and view all the answers

What application is specified for a 2% copper solution?

<p>Irrigation of the nasal sinuses (A)</p> Signup and view all the answers

Besides malleability, what other property is Gold known for?

<p>Most ductile nature (D)</p> Signup and view all the answers

Which of the following is a component of 'Dakin's solution'?

<p>Sodium hypochlorite (B)</p> Signup and view all the answers

Flashcards

Pharmacologic uses of Bismuth

Astringent, mucoprotectant (for peptic ulcer disease), and antiseptic.

Tantalum's surgical use

Used in sheet form for surgical bone repair, it doesn't affect tissues.

Uses of Titanium Oxide (TiO2)

Opacifying agent in capsules, used in contact lenses, and for solar ray protection.

Five Official Gases

Nitrogen, helium, oxygen, carbon dioxide, and nitrous oxide.

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Uses of Selenium Sulfide (SeS2)

Antidandruff and antiseborrheic.

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SO4

A topical anti-inflammatory.

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Stearate

Lubricant.

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Magnesium Oxide (MgO)

Also known as 'Calcinated magnesia' or 'Magnesia'. Component of the universal antidote.

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Universal antidote components

It is composed of Magnesium oxide MgO, Activated charcoal and Tannic acid.

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Magnesium Sulfate (MgSO4)

Also known as 'Epsom salt'. Acts as PO: Laxative and IM: Anticonvulsant.

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Magnesium Sulfate (MgSO4) antidote Use

Antidote for Barium and Barbiturate toxicity.

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Minamata Disease

Mercury toxicity.

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Boron Toxicity

Associated with 'Boiled Lobster Appearance'.

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Hepatic Serosis

Liver damage that can be caused by copper toxicity.

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Aqua Regia

A solution of nitric and hydrochloric acid, optimal for dissolving gold.

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Blue Vitriol

Copper sulfate pentahydrate, a blue-colored compound with various uses.

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Fehling's solution

A solution used to test for reducing sugars; contains copper sulfate.

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Benedict’s solution

A solution used to test for reducing sugars; contains copper sulfate.

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Barfoed’s reagent

A reagent containing copper(II) acetate used to test for monosaccharides.

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Argyria

A condition caused by silver toxicity, resulting in bluish-gray skin discoloration.

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Antidote for Copper Toxicity

The dose of Penicillamine.

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Gypsum

Calcium sulfate; used in dental impressions and surgical casts.

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Zinc

Metal present in insulin; deficiency causes parakeratosis.

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Itai-Itai Disease

Cadmium toxicity, leading to bone and kidney damage.

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Cadmium Sulfide

Yellow sulfide used as an antiseborrheic agent.

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Mercury

Metal; natural source is cinnabar; also known as 'quicksilver'.

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Thallium

Toxicity includes green tongue and alopecia (hair loss).

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Nitrogen

Colorless, odorless, tasteless, inert gas; makes up 71% of air.

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Nitrous Oxide NO2

'Laughing gas'; general anesthetic; stored in a blue container.

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Plumbism

Lead toxicity.

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Silicon

Inhalation can cause silicosis; antidote is aluminum oxide dust inhalation.

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Sodium Acetate

Diuretic, antacid, and alkalinizing agent in Benedict’s solution.

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Sodium Bicarbonate

'Baking Soda'; used as an antacid.

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Sodium Chloride

'Table Salt' or 'Rock Salt'; used as a condiment and in oral rehydration solutions.

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Sodium Biphosphate

'Fleet enema'; stool softener and urinary acidifier for cystitis.

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Sodium Carbonate

Used as an antacid.

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Sodium Hydroxide

'Caustic soda' or 'Lye'; used as a saponifying agent in soap making.

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Sodium Hypochlorite

'Dakin’s solution' or 'Chlorox'; used as a disinfectant and bleaching agent.

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Sodium Thiosulfate

'Photographer’s hypo'; antidote to cyanide poisoning.

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Potassium Chloride

Used in 'Ringer’s solution', 'Darrow’s solution', and as an electrolyte replenisher.

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Potassium Permanganate

'Mineral Chameleon'; volumetric solution and indicator in Permanganometry; antidote for Strychnine poisoning.

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Potassium Bitartrate

'Cream of Tartar' or 'Creamor'; only insoluble salt of Potassium.

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Strong Ammonia Solution

Component of 'Stronger Ammonia Water' and 'Spirit of Hartshorn'.

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Copper

Only reddish-colored metal; 3rd most malleable and 3rd best conductor of electricity.

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Wilson’s Disease

Copper toxicity

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Gold

King of all metals, most malleable and ductile.

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Study Notes

SODIUM

  • Sodium Acetate (NaCHO3) is a diuretic and antacid, and acts as an alkalinizing agent in Benedict's solution.
  • Sodium Bicarbonate (NaHCO3), also known as Baking Soda, is an antacid.
  • Sodium Chloride (NaCl), or Table Salt and Rock Salt, is a condiment and oral rehydrating salt.
  • Sodium Biphosphate (NaH2PO4) functions as a Fleet enema, stool softener, and urinary acidifier for Cystitis.
  • Sodium Carbonate (Na2CO3) in anhydrous form is Soda ash, as a dihydrate is Trona, and as a decahydrate is Sal soda, Washing soda, and Soda crystals; it also acts as an antacid.
  • Sodium Hydroxide (NaOH), also called Caustic soda, Soda, and Lye, is a saponifying agent used in soap making.
  • Sodium Hypochlorite (NaCIO), known as Dakin's solution and Chlorox, functions as a disinfectant and bleaching agent.
  • Sodium Thiosulfate (Na2S2O3), or Photographer's hypo, combined with sodium nitrate, is an antidote for Cyanide poisoning.
  • Sodium Tartrate (NaC4H4O6) is used in the standardization of the Karl Fischer reagent.

POTASSIUM

  • Potassium Chloride (KCl) is Ringer's solution and Darrow's solution, and acts as an electrolyte replenisher.
  • Potassium Permanganate (KMnO4), or Mineral Chameleon, is a volumetric solution and indicator in Permanganometry, It also acts as antidote for Strychnine poisoning.
  • Potassium Bitartrate (KC4H5O6), also known as Cream of Tartar and Creamor, is the only insoluble salt of Potassium.
  • Potassium Ferricyanide Fe(CN)6 is a DOC

AMMONIUM AND AMMONIUM COMPOUNDS

  • Ammonium Ion (NH4) is prepared through the Haber-Bosch process and is a hypothetical alkali metal.
  • Ammonium Chloride (NH4CI), also known as Muriate of Hartshorn and Sal ammoniac (or Salmiac), is a buffer used in zinc analysis (complexation).
  • Strong Ammonia Solution (NH3)), or Stronger Ammonia Water and Spirit of Hartshorn, contains 27-31% Ammonia, used primarily in making ammonia water and is an ingredient of Aromatic spirit of Ammonia.

COPPER

  • Copper is the only reddish-colored metal, is the third most malleable metal and the third best conductor of electricity, and its salts are blue in color.
  • Copper occurs in the respiratory pigments hemocyanin cytochrome oxidase, acts as Protein precipitant, and enhances the absorption of Fe.

THE ALLOYS OF COPPER

  • Bronze is composed of Copper, Tin, and Zinc.
  • Brass is composed of Copper and Zinc.
  • Gun Metal is composed of Copper and Tin.
  • Sterling is composed of Copper and Silver.
  • Devarda's Alloy is composed of Copper, Zinc, and Aluminium.

WILSON'S DISEASE

  • Wilson's Disease is caused by copper toxicity, with symptoms of Hepatic serosis, Jaundice, Bloating, Kidney defects, Brain damage, and Demyelination. Penicillamine (Cuprimine)

COPPER SULFATE (PENTAHYDRATE)

  • Copper Sulfate (CuSO4) known as Blue Vitriol and Blue Stone, is an ingredient in Fehling's solution, Benedict's solution, Barfoed's reagent, and Bordeux mixture.
  • Copper Sulfate is an antidote for Phosphorous poisoning, to be used with Calcium oxide and Water.
  • Copper sulfate also used to treat for vaginitis and 2% irrigate sinus; a 50% female genital tract antiseptic.

SILVER

  • Silver has an oligodynamic action, inhibiting microorganisms in small concentrations.
  • Argyria is silver toxicity and can be treated with NSS Normal Saline Solution, Sodium Thiosulfate (NaC4H4O6), and Potassium Ferricyanide Fe(CN)6.

SILVER PROTEINATES

  • Mild Silver (Ag) is Arygol, which contains 19-25% silver, and acts as an antiseptic for the eyes.
  • Strong Silver (Ag) Proteinates is Protargol, which contains 7.8-8.5% silver; it is a potent germicide for ears, throat, and bladder. Collodial Silver (Ag) is Collargol, which contains 18-22% silver, and acts as a mild antiseptic.

MAGNESIUM

  • Magnesium is the 2nd most abundant intracellular cation and is a metal present in chlorophyll.
  • Magnesium is a component of Grignard reagent.
  • Therapeutic uses of Insoluble compounds act as Gastric antacids, SO4 compound are anticonvulsants, and Conc. SO4 are employed topically topically and as anti-inflammatory; Stearate is a lubricant.
  • Magnesium Oxide (MgO) is known as Calcinated magnesia, Magnesia, and Light magnesia.
  • Magnesium is a component of the universal antidote; Magnesium oxide (MgO), Activated charcoal, and Tannic acid.

MAGNESIUM SULFATE

  • Magnesium Sulfate or MgSO4 which is known as Epsom salt.
  • It is given via PO as a Laxative and via IM as Anticonvulsant.
  • It can act as an Antidote for Barium and Barbiturate toxicity

CALCIUM

  • Calcium is the 2nd most abundant extracellular cation and is the cation of hydrocyapatite
  • Vitamin D is needed for its absorption
  • Natural sources include: Dolomite, Fluorite, and Gypsum (Selenite or Calcium sulfate), Phosphate rock

CALCIUM SULFATE

  • Calcium Sulfate or CaSO4 is also known as Plaster of Paris and Gypsum
  • Acts as diluent in the manufacture of compressed tablets, and used to manufacture dental impressions and surgical casts

ZINC

  • Zinc is a metal present in Insulin
  • Deficiency can lead to Parakeratosis
  • Toxicity can lead to Metal Fume Fever
  • It can countered via Sodium Bicarbonate

CADMIUM

  • Cadmium can cause Itai-Itai Disease
  • Cadmium toxicity is countered via BAL
  • Cadmium Chloride CdCl is for treating Tinea infections
  • Cadmium Sulfide CdS, also known as Yellow sulphide, is anti-seborrheic and known as Capsebon
  • Cadmium Sulfate CdSO4 is an opthalmic antiseptic

MERCURY

  • Mercury is a metal referred to as Hydragyrum, Quicksilver, and Liquid Silver.
  • Its source is Cinnabar
  • Mercury is present in thermometer and amalgams
  • Minamata Disease is toxicity and it's antidote is Sodium formalde sulfoxylate (SFS), BAL and Penicillamine (Cuprimine)

BORON

  • Boron toxicity can lead to "Boiled Lobster Appearance"

ALUMINUM

  • Known as 'Ladd's paste'
  • Aluminum is the 3rd most abundant in all elements and the most abundant in all metals
  • Toxicity can lead to Shaver's Disease
  • Source: Cryolite
  • Uses includes: Antiperspirant deodorant, Gastric antacid but S/E may be Constipation; and as an Antiseptic

ALUM

  • Otherwise referred to as 'Alumina' and is meant for treating Silicosis
  • Two types: Aluminum and Potassium

THALLIUM

  • Thallium Toxicity: leads to Green Tongue and Alopecia

CARBON

  • Carbon has two forms: Crystalline which is Diamond or Graphite; and Amorphous

CARBON DIOXIDE

  • CARBON DIOXIDE CO2 has 210 times affinity to haemoglobin and can lead to asphyxia
  • Death can be prevented by supplying 100% oxygen or if giving Oxygen-helium mixture; it is essential to administer Hyperbaric oxygen

SILICON

  • Silicon has Toxicity: Silicosis
  • It can be treated by inhalation of Aluminum oxide Al2O3 dust

TIN

  • TIN is in the manufacture of cans and utensils
  • Has a Germicidal effect against Staphylococci
  • Used to treat acne and furunculosis

ALLOYS OF TIN

  • PEWTER: 80% Cu + 20% Sn
  • GUN METAL: 90% Cu + 10% Sn
  • ROSE METAL: 50% Bi+ 25% Pb + 25% Sn
  • SOLDER: 50% Pb + 50% Sn

STANNOUS FLOURIDE

  • STANNOUS FLOURIDE SnF2 is in crest toothpaste
  • It is Anticariogenic when making an 8% solution; must be freshly prepared because it can easily oxidized

LEAD

  • LEAD Toxicity: Plumbism occurs when accumulating easily in the GIT and broken skin
  • It is countered with BAL, EDTA (Ethylenediaminetetraacetic acid) and Succimet

BISMUTH

  • Known as 'Beautiful meadow'
  • Used in silvering mirror
  • Pharmacologic use: Astringent, Mucoprotectant (PUD) and as an Antiseptic

TANTALUM

  • TANTALUM is used in sheet form for surgical bone repair
  • It does not affect the tissues

TITANIUM

  • TITANIUM OXIDE TIO2 is an Opacifying agent in capsules
  • used in contact lenses
  • functions as a Solar ray protective in sunblock and suntan lotion

NITROGEN

  • 'without life'
  • 'azote'
  • 'mephitic air'
  • Is a Colorless, odourless, tasteless, INERT GAS
  • It is the Most abundant gas in air (71%)
  • Most stable among the diatomic molecules

NITROUS OXIDE

  • NITROUS OXIDE NO2 also known as 'Laughing gas'
  • Must be Stored in blue container
  • Functions as a General anesthetic but may S/E: cause hypoxia

OXYGEN

  • Also called 'dephlogisticated air'
  • Greek word: 'acid-former'

THREE ALLOTROPES

  • Three forms: Nascent, Molecular, and Ozone

FIVE OFFICIAL GASES

  • Nitrogen, Helium, Oxygen, Carbon dioxide and Nitrous oxide

SELENIUM

  • Selenium Functions as an Antioxidant
  • Acts Synergistic with Vitamin E
  • Functions as an Important trace element

SELENIUM SULFIDE

  • SELENIUM SULFIDE SeS2 or 'Selsun blue' is used as an Antidandruff and treat Seborrheic

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