Wound Healing Process

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What is the role of neutrophils in the inflammation phase?

Amplify inflammatory response by release of cytokines, reduce infection by bacterial killing, and debride damaged tissue

What occurs in the immediate phase of haemostasis?

Platelets aggregate at the wound and release inflammatory mediators

What is the main activity during the proliferation phase?

Fibroblasts migrate into the wound and synthesize collagen

What stimulates angiogenesis during the proliferation phase?

Hypoxia and cytokines

What occurs during the remodelling phase?

Reorientation and maturation of collagen fibers increase wound strength

What is the main activity of fibroblasts during the proliferation phase?

Synthesizing collagen

What is the role of thrombus formation in achieving haemostasis?

Stopping bleeding by forming a blood clot

What is the function of myofibroblasts during the proliferation phase?

Causing wound contraction

What is the main role of macrophages during the inflammation phase?

Secreting cytokines, growth factors, and collagenases

What stimulates angiogenesis during the proliferation phase?

Hypoxia and cytokines

Test your knowledge of the stages of wound healing, from haemostasis to inflammation

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