Wound Healing: Dr. Dastan Tahir Abdallah - Surgery 1
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Questions and Answers

What is a wound?

A break in the integrity of the skin or tissues.

How many distinct processes are involved in the healing process?

2

Define regeneration in the context of healing.

Healing by proliferation of parenchymal cells, resulting in complete restoration of the original tissues.

What is repair in the healing process?

<p>A healing outcome where tissues do not return to their normal architecture and function.</p> Signup and view all the answers

What are the types of wounds based on Rank and Wakefield classification?

<p>Tidy wounds and untidy wounds.</p> Signup and view all the answers

List three types of wounds based on their characteristics.

<p>Clean incised wound, lacerated wound, bruising and contusion.</p> Signup and view all the answers

What is the role of osteoclasts in hard tissue healing?

<p>To debride necrotic bone from the wound margin.</p> Signup and view all the answers

When does new bone formation become apparent after surgery?

<p>About 6 days after surgery.</p> Signup and view all the answers

What happens during stage one of tooth socket healing?

<p>Blood clotting begins.</p> Signup and view all the answers

What occurs during stage two of tooth socket healing?

<p>The attention turns to the clot that has formed in the tooth's socket.</p> Signup and view all the answers

When does the gum tissue begin to close around the extraction site?

<p>Roughly 72 hours after removal.</p> Signup and view all the answers

When does the final healing stage occur in tooth socket healing?

<p>Around seven to ten days after the procedure.</p> Signup and view all the answers

What are some general factors that can affect wound healing?

<p>Age, obesity, smoking, malnutrition, zinc/copper deficiency, vitamin deficiency (Vit C, Vit A), anemia</p> Signup and view all the answers

Name some complications of wound healing related to deficient scar formation.

<p>Wound dehiscence and ulceration</p> Signup and view all the answers

What are some factors affecting wound healing related to malignancy?

<p>Malignancy can affect wound healing, along with other factors such as jaundice, diabetes, HIV, and immunosuppressive diseases.</p> Signup and view all the answers

List some complications of wound healing associated with excessive repair component formation.

<p>Hypertrophic scar, keloid, excessive granulation tissue</p> Signup and view all the answers

Which drugs can affect wound healing?

<p>Bisphosphonates, glucocorticoids (Cortisol), NSAIDs (COX 1), Cyclooxygenase-2 inhibitors</p> Signup and view all the answers

Give examples of factors that can lead to poor wound healing.

<p>Large defect or poor apposition, recurrent trauma, irradiated area, underlying diseases like osteomyelitis and malignancy</p> Signup and view all the answers

Describe the main difference between healing by first intention and healing by second intention.

<p>Healing by first intention involves wounds with opposed edges and minimal loss of cells and tissue, while healing by second intention involves wounds with separated edges and extensive loss of cells and tissue.</p> Signup and view all the answers

What is the key characteristic of healing by first intention?

<p>The narrow incisional space immediately fills with clotted blood containing fibrin and blood cells, forming a scab that covers the wound.</p> Signup and view all the answers

How does healing by second intention differ from healing by first intention?

<p>Healing by second intention involves more extensive loss of cells and tissue, leading to the formation of abundant granulation tissue for repair.</p> Signup and view all the answers

Explain the process of wound healing by second intention.

<p>Wounds with separated edges and extensive loss of cells and tissue lead to the regeneration of parenchymal cells and abundant granulation tissue growth for repair.</p> Signup and view all the answers

What are the key differences between hard tissue healing and soft tissue healing?

<p>In hard tissue healing, the maturation phase differs markedly due to the type of tissue involved.</p> Signup and view all the answers

List three characteristics that differentiate healing by first intention from healing by second intention.

<ol> <li>Wounds with opposed edges vs. wounds with separated edges</li> <li>Minimal loss of cells and tissue vs. extensive loss</li> <li>Sutures to approximate edges vs. abundant granulation tissue growth</li> </ol> Signup and view all the answers

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