Wound Healing Complications Overview
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Questions and Answers

What is a common obstacle to fracture healing?

  • Adequate blood supply
  • Insufficient scar formation
  • Proper immobilization of the fracture
  • Excessive scar formation (correct)

Which anatomical factor can lead to poor blood supply and impair fracture healing?

  • Unimpaired nutrient artery
  • Fracture through an area devoid of periosteum (correct)
  • Adequate adjacent soft tissue
  • Fracture of the distal phalanx

What is the term used to describe a false joint that may develop at the fracture site if the fractured bone is not properly immobilized?

  • Keloid
  • Desmoid
  • Hypertrophic scar
  • Pseudo-arthrosis (correct)

What is the term used to describe a fracture that does not unite within the expected timeframe?

<p>Non-union (C)</p> Signup and view all the answers

Which of the following is a potential cause of delayed union of a fracture?

<p>Malnutrition (A)</p> Signup and view all the answers

What type of callus is associated with a non-union fracture?

<p>Atrophic avascular callus (B)</p> Signup and view all the answers

What is the main step involved in the formation of a stable fibrous scar?

<p>Deposition of connective tissue (D)</p> Signup and view all the answers

What is the role of VEGF in the angiogenesis process?

<p>Causes vasodilation and increased permeability (C)</p> Signup and view all the answers

What is the role of PDGF in the deposition of connective tissue?

<p>Recruits pericytes and smooth muscle cells to the new blood vessels (C)</p> Signup and view all the answers

Which of the following is a potential consequence of inadequate angiogenesis?

<p>Ulceration (D)</p> Signup and view all the answers

What is the role of TGF-β in the deposition of connective tissue?

<p>Induces the production of ECM proteins by fibroblasts (D)</p> Signup and view all the answers

Which of the following is NOT a potential consequence of excessive scar formation?

<p>Improved angiogenesis (D)</p> Signup and view all the answers

What is the main characteristic of a hypertrophic scar?

<p>It involves excessive collagen deposition. (B)</p> Signup and view all the answers

How is exuberant granulation tissue different from a typical healing process?

<p>It blocks re-epithelialization and protrudes above surrounding skin. (C)</p> Signup and view all the answers

What characterizes a keloid in terms of tissue growth?

<p>Keloids grow and progress beyond the boundaries of the original wound. (B)</p> Signup and view all the answers

Which condition involves aggressive proliferation of fibroblasts and connective tissue elements?

<p>Desmoids or aggressive fibromatosis (B)</p> Signup and view all the answers

What is the main implication of inadequate angiogenesis during healing of wounds?

<p>Ulceration due to insufficient healing (C)</p> Signup and view all the answers

What factor contributes to the formation of a hypertrophic scar?

<p>Excessive collagen deposition (B)</p> Signup and view all the answers

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