Wound Healing Complications Overview

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What is a common obstacle to fracture healing?

Adequate blood supply

Insufficient scar formation

Proper immobilization of the fracture

Excessive scar formation (correct)

Which anatomical factor can lead to poor blood supply and impair fracture healing?

Unimpaired nutrient artery

Fracture through an area devoid of periosteum (correct)

Adequate adjacent soft tissue

Fracture of the distal phalanx

What is the term used to describe a false joint that may develop at the fracture site if the fractured bone is not properly immobilized?

Keloid

Desmoid

Hypertrophic scar

Pseudo-arthrosis (correct)

What is the term used to describe a fracture that does not unite within the expected timeframe?

Non-union Signup and view all the answers

Which of the following is a potential cause of delayed union of a fracture?

Malnutrition Signup and view all the answers

What type of callus is associated with a non-union fracture?

Atrophic avascular callus Signup and view all the answers

What is the main step involved in the formation of a stable fibrous scar?

Deposition of connective tissue Signup and view all the answers

What is the role of VEGF in the angiogenesis process?

Causes vasodilation and increased permeability Signup and view all the answers

What is the role of PDGF in the deposition of connective tissue?

Recruits pericytes and smooth muscle cells to the new blood vessels Signup and view all the answers

Which of the following is a potential consequence of inadequate angiogenesis?

Ulceration Signup and view all the answers

What is the role of TGF-β in the deposition of connective tissue?

Induces the production of ECM proteins by fibroblasts Signup and view all the answers

Which of the following is NOT a potential consequence of excessive scar formation?

Improved angiogenesis Signup and view all the answers

What is the main characteristic of a hypertrophic scar?

It involves excessive collagen deposition. Signup and view all the answers

How is exuberant granulation tissue different from a typical healing process?

It blocks re-epithelialization and protrudes above surrounding skin. Signup and view all the answers

What characterizes a keloid in terms of tissue growth?

Keloids grow and progress beyond the boundaries of the original wound. Signup and view all the answers

Which condition involves aggressive proliferation of fibroblasts and connective tissue elements?

Desmoids or aggressive fibromatosis Signup and view all the answers

What is the main implication of inadequate angiogenesis during healing of wounds?

Ulceration due to insufficient healing Signup and view all the answers

What factor contributes to the formation of a hypertrophic scar?

Excessive collagen deposition Signup and view all the answers