Podcast
Questions and Answers
What is the primary function of phagocytes?
What is the primary function of phagocytes?
- Produce antibodies
- Transport oxygen
- Regulate blood pressure
- Engulf pathogens (correct)
How long do monocytes spend in the marrow before maturing in tissues?
How long do monocytes spend in the marrow before maturing in tissues?
- 1-3 hours
- 1-2 days
- 20-40 hours (correct)
- Several weeks
Which type of blood cell is known for its large central oval or indented nucleus?
Which type of blood cell is known for its large central oval or indented nucleus?
- Eosinophil
- Monocyte (correct)
- Lymphocyte
- Granulocyte
What condition is characterized by an increased number of lymphocytes?
What condition is characterized by an increased number of lymphocytes?
Which type of granulocyte is known for being redder in concentration?
Which type of granulocyte is known for being redder in concentration?
Which of the following best describes the appearance of the cytoplasm in monocytes?
Which of the following best describes the appearance of the cytoplasm in monocytes?
What is the role of granulocytes in relation to parasites?
What is the role of granulocytes in relation to parasites?
Leucocytosis refers to which condition?
Leucocytosis refers to which condition?
What is the primary feature of neutrophil leucocytosis?
What is the primary feature of neutrophil leucocytosis?
Which condition is associated with an increase in eosinophils lasting more than six months?
Which condition is associated with an increase in eosinophils lasting more than six months?
What is the typical cause of monocytosis?
What is the typical cause of monocytosis?
What condition might be marked by the presence of immature cells in the peripheral blood?
What condition might be marked by the presence of immature cells in the peripheral blood?
Which clinical feature is commonly associated with neutropenia?
Which clinical feature is commonly associated with neutropenia?
Which factor could potentially lead to drug-induced neutropenia?
Which factor could potentially lead to drug-induced neutropenia?
What type of leucocytosis is characterized by toxic granulation and Doehle bodies?
What type of leucocytosis is characterized by toxic granulation and Doehle bodies?
What is a common cause of basophil leucocytosis?
What is a common cause of basophil leucocytosis?
What is one of the main treatments for autoimmune neutropenia?
What is one of the main treatments for autoimmune neutropenia?
Which type of leukocyte is primarily responsible for assisting phagocytes in the body's defense?
Which type of leukocyte is primarily responsible for assisting phagocytes in the body's defense?
What is the most common cause of lymphocytosis in infants and young children?
What is the most common cause of lymphocytosis in infants and young children?
Which of the following cells is NOT involved in the immune response when the body encounters an EBV infection?
Which of the following cells is NOT involved in the immune response when the body encounters an EBV infection?
During the maturation process of T cells, which specific type of T cells are eliminated?
During the maturation process of T cells, which specific type of T cells are eliminated?
Which of the following is NOT a diagnostic test for Infectious Mononucleosis?
Which of the following is NOT a diagnostic test for Infectious Mononucleosis?
Which of the following is a common cause of lymphopenia?
Which of the following is a common cause of lymphopenia?
Flashcards
Leucogenesis
Leucogenesis
The process of producing white blood cells (leukocytes) from stem cells in the bone marrow.
Phagocytes
Phagocytes
Cells that engulf and digest pathogens or debris; include granulocytes and monocytes.
Granulocytes
Granulocytes
A type of phagocyte with granules in their cytoplasm; includes neutrophils, eosinophils, and basophils.
Monocytes
Monocytes
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Leucocytosis
Leucocytosis
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Lymphocytosis
Lymphocytosis
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Neutropenia
Neutropenia
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Lymphopenia
Lymphopenia
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Phagocytosis
Phagocytosis
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Chemotaxis
Chemotaxis
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Neutrophil leucocytosis
Neutrophil leucocytosis
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Eosinophil leucocytosis
Eosinophil leucocytosis
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Basophil leucocytosis
Basophil leucocytosis
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Monocytosis
Monocytosis
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Hematopoietic growth factor (G-CSF)
Hematopoietic growth factor (G-CSF)
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Langerhans cell histiocytosis
Langerhans cell histiocytosis
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Monocytes confusion
Monocytes confusion
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T cell maturation
T cell maturation
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Paul-Bunnel test
Paul-Bunnel test
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Study Notes
WBC and Benign Disorders
- WBCs are crucial for the body's defense mechanisms
- Learning guidelines include leucogenesis, phagocytes, granulocytes, and monocytes.
- Immunocytes, lymphocytosis, and lymphopenia are also discussed.
- Lymphadenopathy is also a key topic.
- WBCs are produced in the bone marrow. The process of WBC production is called leucogenesis.
- There are various types of WBCs and each has its unique function
- Phagocytes engulf harmful pathogens by phagocytosis
- Phagocytosis – engulf harmful pathogens
- Granulopoiesis: Production of granulocytes (neutrophils, eosinophils, basophils) in the bone marrow.
- Immunocytes (lymphocytes) respond to specific foreign invaders
- Lymphocytes and their development are central to the immune system
- Monocytes
- Larger than other peripheral blood leukocytes.
- Have a large central oval or indented nucleus with clumped chromatin.
- Cytoplasm stains blue with vacuoles.
- A short amount of time in the marrow before migrating to tissues for function.
- Macrophages are derived from monocytes and play a critical role in immune responses and tissue repair.
- Phagocytes engulf harmful pathogens by phagocytosis
- Granulocytes (neutrophils, eosinophils, basophils)
- Neutrophils (highest number)
- Phagocytic cells prevalent in acute inflammation.
- Do not exist in healthy tissues.
- Vital participants in inflammatory processes.
- Eosinophils (2-3% of leukocytes):
- Combat parasites and involved in allergic reactions.
- Basophils (1%):
- Important in allergic reactions.
- Neutrophils (highest number)
- Benign disorders of granulocytes and monocytes encompass various conditions.
- Leucocytosis & Monocytosis:
- Increased WBC numbers due to inflammation
- Neutropenia:
- Decreased neutrophil count. Infections commonly occur in these cases.
- Histiocytic Disorders:
- Disorders of the cells related to phagocytes.
- Leucocytosis & Monocytosis:
- Lymphocytes:
- Immunocytes – play an essential role in immune responses
- Lymphocytosis:
- Increased lymphocyte count. Infections are usually the cause
- Infections Mononucleosis:
- Infectious mononucleosis is caused by the Epstein-Barr virus (EBV).
- Lymphopenia:
- Decreased lymphocyte count
- Lymphadenopathy:
Swollen lymph nodes. The causes can be localized or generalized
- Can result from infections, cancers, or other conditions.
- Quantitative changes in WBCs are classified as cytopenia (decreased number) and cytosis (increased number)
- Qualitative tests include morphology and functional changes
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