Watson–Crick Model and DNA Replication

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What does the semiconservative model of DNA replication produce?

Two hybrid molecules of old and new strands

Why was ultracentrifugation used in the Meselson–Stahl experiment?

To separate molecules with different densities

What would be the outcome of a third round of replication in the Meselson–Stahl experiment?

The light 14N band would be darker due to hybrid molecules producing one hybrid and one all-14N molecule

What was the heavier isotope of nitrogen used by Meselson and Stahl in their experiment?

15N

Why did bacteria grown in heavy 15N medium have denser DNA than bacteria grown in 14N medium?

Due to the incorporation of the heavy 15N isotope into the bases of DNA

What does the Watson-Crick model suggest about copying genetic information?

Complementarity is the basis for copying genetic information.

In which DNA replication model do both daughter strands contain all-new molecules?

Conservative model

How are the daughter duplexes formed in the semiconservative model?

Each daughter duplex consists of one parental strand and one newly synthesized strand.

What characterizes the dispersive model of DNA replication?

New DNA consists of mixtures of parental and newly synthesized strands.

What happens to the parental helix in the conservative DNA replication model?

Remains intact

Explore the Watson–Crick model of DNA structure and the process of DNA replication. Learn how the complementarity of DNA bases allows for accurate copying of genetic information from parental strands to daughter strands. Test your knowledge on the key concepts of DNA replication.

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