Water-Soluble Vitamins Overview Quiz
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Questions and Answers

Which of the following is a characteristic of water-soluble vitamins?

  • They can be stored in the body
  • They are essential for normal health and growth (correct)
  • They are soluble in fat solvents
  • They need bile salts for absorption
  • Which vitamin is a provitamin that can be converted into Vitamin A inside the body?

  • Vitamin C
  • Vitamin E
  • Vitamin D (correct)
  • Vitamin B
  • Which vitamins are classified as fat soluble?

  • Vitamin C
  • Vitamin B complex group
  • Vitamin C and K
  • Vitamin D and E (correct)
  • What is the main characteristic of fat-soluble vitamins?

    <p>They can be stored in the body</p> Signup and view all the answers

    What are precursors of vitamins that can be converted into vitamins inside the body called?

    <p>Provitamins</p> Signup and view all the answers

    What is the main cause of the formation of ketone bodies (KB) in the fasting state?

    <p>Increased acetylCoA accumulation</p> Signup and view all the answers

    Which enzyme is considered the key enzyme of ketogenesis?

    <p>HMG-CoA lyase</p> Signup and view all the answers

    What is the main fate of ketone bodies in extrahepatic tissues?

    <p>Utilization as fuel</p> Signup and view all the answers

    Which condition leads to the increased formation of ketone bodies?

    <p>Hypoglycemia</p> Signup and view all the answers

    During ketolysis, what is the main fate of acetoacetate picked up from the blood in the mitochondria?

    <p>Activation to form acetyl CoA</p> Signup and view all the answers

    Which enzyme is responsible for the oxidation of 3-hydroxybutyrate to acetoacetate in extrahepatic tissues?

    <p>Thiophorase enzyme</p> Signup and view all the answers

    Which tissue lacks the enzyme necessary for metabolizing ketone bodies?

    <p>Liver</p> Signup and view all the answers

    What is the fate of acetone, a minor side product of ketone bodies?

    <p>It is lost in expired air at lungs and in urine</p> Signup and view all the answers

    In which condition do patients with type 1 insulin-dependent diabetes mellitus (DM) develop ketoacidosis?

    <p>When fatty acid release from adipose tissue exceeds ketone synthesis in the liver</p> Signup and view all the answers

    Why are patients with type II non–insulin-dependent diabetes mellitus (NIDDM) much less likely to show ketoacidosis?

    <p>Insulin resistance in the periphery is not complete</p> Signup and view all the answers

    Study Notes

    Vitamins

    • Water-soluble vitamins are characterized by being easily excreted in urine, non-toxic, and not stored in the body.
    • Vitamin A is a provitamin that can be converted into Vitamin A inside the body.
    • Vitamins A, D, E, and K are classified as fat-soluble vitamins.
    • The main characteristic of fat-soluble vitamins is that they are stored in the body and can be toxic in high doses.

    Ketogenesis

    • The main cause of the formation of ketone bodies (KB) in the fasting state is the breakdown of fatty acids in the liver.
    • The enzyme HMG-CoA synthase is considered the key enzyme of ketogenesis.
    • In extrahepatic tissues, ketone bodies are primarily used as an energy source.

    Ketolysis

    • During ketolysis, acetoacetate is converted into acetyl-CoA, which is then used in the citric acid cycle.
    • The enzyme 3-hydroxybutyrate dehydrogenase is responsible for the oxidation of 3-hydroxybutyrate to acetoacetate in extrahepatic tissues.
    • The brain is the tissue that lacks the enzyme necessary for metabolizing ketone bodies.

    Ketoacidosis

    • Acetone, a minor side product of ketone bodies, is exhaled through the lungs.
    • Patients with type 1 insulin-dependent diabetes mellitus (DM) develop ketoacidosis when they have low insulin levels and high glucagon levels, leading to increased glucose production and ketone body formation.
    • Patients with type II non–insulin-dependent diabetes mellitus (NIDDM) are much less likely to show ketoacidosis due to their insulin resistance, which leads to higher insulin levels and lower glucagon levels.

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    Description

    Test your knowledge on water-soluble vitamins and coenzymes with this quiz. Explore the classifications, functions, and associated pathologies of water-soluble vitamins.

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