Podcast
Questions and Answers
What is the first-line treatment for Aspergillosis, according to the provided information?
What is the first-line treatment for Aspergillosis, according to the provided information?
- Caspofungin
- Voriconazole (correct)
- Amphotericin B
- Fluconazole
A geriatric patient weighing 45kg is prescribed Voriconazole for Aspergillosis. Considering the maximum FDA-approved oral dosage, what is the appropriate daily dose?
A geriatric patient weighing 45kg is prescribed Voriconazole for Aspergillosis. Considering the maximum FDA-approved oral dosage, what is the appropriate daily dose?
- 600mg (correct)
- 12mg/kg
- 800mg
- 300mg
A patient weighing 35kg is prescribed Voriconazole. What is the maximum FDA-approved oral daily dosage?
A patient weighing 35kg is prescribed Voriconazole. What is the maximum FDA-approved oral daily dosage?
- 300mg (correct)
- 800mg
- 12mg/kg
- 600mg
What consideration should be taken with regards to food intake when administering oral Voriconazole?
What consideration should be taken with regards to food intake when administering oral Voriconazole?
Which of the following statements regarding Voriconazole dosing is correct?
Which of the following statements regarding Voriconazole dosing is correct?
Flashcards
Voriconazole (Vfend)
Voriconazole (Vfend)
An antifungal medication used primarily to treat Aspergillosis.
Dosage for 40kg+
Dosage for 40kg+
For patients 40kg or more, the max dose is 12mg/kg/day IV or 600mg/day PO, up to 800mg off-label.
Dosage for 40kg-
Dosage for 40kg-
For patients 40kg or less, the max dose is 12mg/kg/day IV or 300mg/day PO, up to 800mg off-label.
PO administration
PO administration
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Renal dose adjustment
Renal dose adjustment
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Study Notes
Voriconazole (Vfend) Dosage Information
- Voriconazole is available as an intravenous (IV) medication, and in oral tablet, capsule, and liquid suspension forms.
- It's a first-line treatment for aspergillosis.
- Maximum dosage varies based on patient weight.
Geriatric Dosage Guidelines
-
40 kg or more:
- IV: 12 mg/kg/day
- Oral (PO): FDA-approved maximum is 600 mg/day, but doses up to 800 mg/day have been used off-label.
-
40 kg or less:
- IV: 12 mg/kg/day
- Oral (PO): FDA-approved maximum is 300 mg/day, but doses up to 800 mg/day have been used off-label.
Important Considerations for Oral Administration
- Take oral formulations at least one hour before or after meals.
Renal Dose Adjustment
- No standard renal dose adjustment is typically necessary.
- However, creatinine clearance (CrCl) should be considered in certain cases.
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Description
This quiz covers essential dosage information for Voriconazole (Vfend), a first-line treatment for aspergillosis. It includes geriatric dosage guidelines, oral administration considerations, and renal dose adjustments. Test your knowledge on the various forms and maximum dosages based on patient weight.
