AmB vs Voriconazole
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Questions and Answers

Which type of cancer patients have a high risk of invasive fungal infection?

  • Autologous HSCT with mucoritis
  • AML/MDS (neutropenic)
  • Allogenic HSCT with GVHD
  • All of the above (correct)
  • Which anti-fungal class is recommended for breakthrough infections?

  • LAMB
  • Fluconazole
  • Echinocandin
  • Isavuconazole/voriconazole (correct)
  • What is the recommended prophylaxis for invasive aspergillosis (IA) in cancer patients?

  • LAMB
  • Posaconazole
  • Voriconazole
  • Isavuconazole (correct)
  • What diagnostic test is used to confirm invasive fungal infection?

    <p>All of the above</p> Signup and view all the answers

    What is the recommended duration for Isavuconazole treatment for invasive aspergillosis?

    <p>3 months</p> Signup and view all the answers

    Match the following terms with their definitions:

    <p>AmB = An antifungal medication Voriconazole = An antifungal medication used in the treatment of invasive aspergillosis Probable (Galactomannan +ve, HRCT +ve) = A probable diagnosis of invasive fungal infection Invasive Aspergillosis (IA) = A type of invasive fungal infection</p> Signup and view all the answers

    Match the following treatments with their uses:

    <p>LAMB = Used for empiric treatment of invasive fungal infection Echinocandin = Used for breakthrough infections Voriconazole = Used for prophylaxis Isavuconazole = Used in combination with LAMB for treatment of invasive fungal infection</p> Signup and view all the answers

    Match the following conditions with their risk levels for invasive fungal infection:

    <p>ALL Autologus with mucoritis = High risk Allogenic HSCT (neutropenic) = High risk AML/MDS (neutropenic) = High risk Allogenic HSCT with GVHD = High risk</p> Signup and view all the answers

    Match the following terms with their definitions:

    <p>Pre-emptive/Targeted = A treatment approach for invasive fungal infection Proven Histopathology/Culture +ve) = A confirmed diagnosis of invasive fungal infection Patient not responding to broad spectrum antibiotics for 4 days = Possible invasive fungal infection Fluconazole/Echinocandin = Used for prophylaxis in low to intermediate risk patients</p> Signup and view all the answers

    Match the following treatments with their durations:

    <p>Isavuconazole = Duration: 3 Months Voriconazole Prophylaxis = Duration: varies based on individual patient LAMB + Isavuconazole = Duration: varies based on individual patient Posaconazole = Duration: varies based on individual patient</p> Signup and view all the answers

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