AmB vs Voriconazole

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Questions and Answers

Which type of cancer patients have a high risk of invasive fungal infection?

Autologous HSCT with mucoritis
AML/MDS (neutropenic)
Allogenic HSCT with GVHD
All of the above (correct)

Which anti-fungal class is recommended for breakthrough infections?

LAMB
Fluconazole
Echinocandin
Isavuconazole/voriconazole (correct)

What is the recommended prophylaxis for invasive aspergillosis (IA) in cancer patients?

LAMB
Posaconazole
Voriconazole
Isavuconazole (correct)

What diagnostic test is used to confirm invasive fungal infection?

All of the above (D) Signup and view all the answers

What is the recommended duration for Isavuconazole treatment for invasive aspergillosis?

3 months (B) Signup and view all the answers

Match the following terms with their definitions:

AmB = An antifungal medication Voriconazole = An antifungal medication used in the treatment of invasive aspergillosis Probable (Galactomannan +ve, HRCT +ve) = A probable diagnosis of invasive fungal infection Invasive Aspergillosis (IA) = A type of invasive fungal infection Signup and view all the answers

Match the following treatments with their uses:

LAMB = Used for empiric treatment of invasive fungal infection Echinocandin = Used for breakthrough infections Voriconazole = Used for prophylaxis Isavuconazole = Used in combination with LAMB for treatment of invasive fungal infection Signup and view all the answers

Match the following conditions with their risk levels for invasive fungal infection:

ALL Autologus with mucoritis = High risk Allogenic HSCT (neutropenic) = High risk AML/MDS (neutropenic) = High risk Allogenic HSCT with GVHD = High risk Signup and view all the answers

Match the following terms with their definitions:

Pre-emptive/Targeted = A treatment approach for invasive fungal infection Proven Histopathology/Culture +ve) = A confirmed diagnosis of invasive fungal infection Patient not responding to broad spectrum antibiotics for 4 days = Possible invasive fungal infection Fluconazole/Echinocandin = Used for prophylaxis in low to intermediate risk patients Signup and view all the answers

Match the following treatments with their durations:

Isavuconazole = Duration: 3 Months Voriconazole Prophylaxis = Duration: varies based on individual patient LAMB + Isavuconazole = Duration: varies based on individual patient Posaconazole = Duration: varies based on individual patient Signup and view all the answers

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