Vitamins and Water

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Questions and Answers

In elderly individuals, an impaired sense of thirst can directly affect which physiological parameter regulated by water intake?

  • Maintenance of electrolyte balance in intracellular fluids
  • Blood volume, potentially leading to dehydration (correct)
  • Body temperature regulation during exercise
  • Digestion and absorption of fat-soluble vitamins

Why are fat-soluble vitamins more likely to cause toxicity than water-soluble vitamins?

  • They do not require binding proteins for transport in the blood.
  • They are stored in the liver and fatty tissues, leading to accumulation. (correct)
  • They are metabolized more quickly in the kidneys.
  • They are more readily excreted through urine.

How does Vitamin E protect cells from damage?

  • By directly stimulating the production of collagen
  • By acting as an antioxidant to neutralize free radicals (correct)
  • By enhancing the absorption of minerals in the intestines
  • By promoting the synthesis of clotting factors in the liver

If a patient has a deficiency in Vitamin K, which bodily function would be most directly affected?

<p>Blood clotting and coagulation (A)</p> Signup and view all the answers

Given its role in collagen synthesis, which symptom might directly indicate a Vitamin C deficiency?

<p>Poor wound healing (C)</p> Signup and view all the answers

The Vitamin B complex is essential for RBC (red blood cell) production. What other process is directly supported by Vitamin B complex?

<p>Energy metabolism and DNA synthesis (B)</p> Signup and view all the answers

How do minerals contribute to nerve conduction?

<p>By maintaining the electrochemical gradients necessary for nerve impulse transmission (A)</p> Signup and view all the answers

Why is glycogen important for tissue and brain function?

<p>It serves as an immediate energy reserve, maintaining glucose levels during fasting. (A)</p> Signup and view all the answers

How do dietary fats facilitate the absorption and transport of certain vitamins in the body?

<p>By encapsulating vitamins in micelles, which enhance their solubility (D)</p> Signup and view all the answers

In what scenario would the body utilize protein as an energy source?

<p>When carbohydrate and fat stores are depleted. (A)</p> Signup and view all the answers

What physiological implication is indicated by elevated prealbumin levels?

<p>Rapidly improving nutritional status. (B)</p> Signup and view all the answers

How does the decreased kidney function indicated by increased creatinine levels affect drug dosages?

<p>Decreasing drug dosages to prevent drug accumulation and toxicity. (C)</p> Signup and view all the answers

How does the body compensate for decreased bone density due to vitamin D deficiency?

<p>By activating the parathyroid gland to release calcium from bones. (A)</p> Signup and view all the answers

Which physiological process is most immediately compromised by an electrolyte imbalance, as reflected in abnormal potassium levels?

<p>Cardiac and muscle cell excitability. (D)</p> Signup and view all the answers

How does anemia, resulting from low hemoglobin levels, primarily impact tissue oxygenation at the cellular level?

<p>By reducing the amount of oxygen delivered to cells. (C)</p> Signup and view all the answers

How can the 3-month average blood glucose level, indicated by hemoglobin A1c, guide adjustments in a patient’s diabetes management plan?

<p>By demonstrating long-term glycemic control, informing medication or lifestyle adjustments. (D)</p> Signup and view all the answers

How does inflammation directly impede the initial stages of wound healing?

<p>By causing vasoconstriction and reducing oxygen supply to the wound (C)</p> Signup and view all the answers

Why is oxygenation and tissue perfusion critical for effective wound healing?

<p>They supply the necessary nutrients and immune cells to the wound site. (D)</p> Signup and view all the answers

How does diabetes mellitus impair the wound healing process at the cellular level?

<p>By causing endothelial dysfunction and impaired angiogenesis. (C)</p> Signup and view all the answers

What is the primary risk associated with undermining in wound management?

<p>Potential for increased dead space and infection. (D)</p> Signup and view all the answers

How does slough affect wound healing?

<p>It consumes available oxygen, impairing angiogenesis. (A)</p> Signup and view all the answers

What is the key distinction between slough and necrotic tissue in wound assessment?

<p>Slough is typically moist and stringy, whereas necrotic tissue is frequently dry and hard. (B)</p> Signup and view all the answers

Why is it critical to address wound tunneling promptly in wound care management?

<p>To mitigate the risk of deep tissue infection and abscess formation. (D)</p> Signup and view all the answers

What are the primary mechanisms by which negative pressure wound therapy (NPWT) enhances wound healing?

<p>By stimulating angiogenesis, reducing edema, and removing exudate. (A)</p> Signup and view all the answers

In sharp debridement, what constitutes informed consent?

<p>Detailing the method's risks, benefits, and alternatives. (C)</p> Signup and view all the answers

In wound measurement, why is there a need to measure the length, width, and depth?

<p>To assess the extent of the wound and monitor healing progress. (B)</p> Signup and view all the answers

When describing the wound bed, what is the significance of granulation tissue?

<p>It is healthy tissue that is formed in the remodeling phase. (B)</p> Signup and view all the answers

What is the clinical significance of serosanguineous exudate in wound assessment?

<p>It is a normal finding in the early stages of wound healing, indicating a mix of serous fluid and blood. (C)</p> Signup and view all the answers

What clinical action is directly indicated by purulent exudate from a wound site?

<p>Initiation of systemic antibiotic therapy and wound culture. (A)</p> Signup and view all the answers

What clinical marker distinguishes arterial ulcers from venous ulcers?

<p>Arterial ulcers are characterized by diminished or absent pulses. (D)</p> Signup and view all the answers

How does impaired circulation typically manifest at the wound edges?

<p>Pale or dusky color with rolled or epibolic edges. (B)</p> Signup and view all the answers

How should a nurse approach documenting peri-wound skin changes such as redness or edema?

<p>Document the presence, extent, and characteristics of these changes meticulously. (D)</p> Signup and view all the answers

What implication does a peri-wound skin that is macerated suggest?

<p>Tissue softening due to excessive moisture exposure. (A)</p> Signup and view all the answers

Why is pain assessment such a critical component of wound management?

<p>To evaluate the effectiveness of pain management strategies and their impact on healing progress. (A)</p> Signup and view all the answers

Why is the assessment of wound odor critical in wound management?

<p>To immediately identify infection and select an appropriate treatment. (B)</p> Signup and view all the answers

What is the underlying reason the odor must be assessed AFTER the wound cleansing?

<p>To remove transient odors due to exudate and debris and make the actual infection more apparent. (B)</p> Signup and view all the answers

Flashcards

Water's Role

Helps regulate body temperature, pH balance, and fluid/electrolyte balance.

Fat-Soluble Vitamins

Vitamins stored in the liver and fatty tissue; can accumulate in the body.

Water-Soluble Vitamins

Vitamins that must be replenished regularly.

Vitamin A

Important for vision, infection resistance, and skin integrity.

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Vitamin D

Helps with bone and tissue formation.

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Vitamin E

Acts as an antioxidant to protect cells.

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Vitamin K

Essential for blood clotting and coagulation.

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Vitamin C

Helps with collagen synthesis, wound healing, and antibody development.

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Vitamin B Complex

Supports RBC production, energy metabolism, and DNA synthesis.

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Minerals

Needed for bone tissue and teeth maintenance, nerve conduction, and muscle/blood vessel contraction.

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Carbohydrates

The body's main energy source.

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Glycogen

Necessary for tissue and brain function.

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Fats

Provide energy, support/insulate organs/nerves, help absorb/transport vitamins, and contribute to cell membrane structure.

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Protein

Necessary for development, maintenance, and repair of body tissues.

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Glucose (Lab value)

Measures the amount of glucose in the blood; indicates energy source and brain function.

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Prealbumin

Short-term marker for nutrition (protein).

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Albumin

Long-term marker for nutrition (protein).

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Hemoglobin

RBC Count- Oxygen Carrying Capacity

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Inflammation (Wound Healing)

Wound healing stage (2-5 days) focused on removing debris and preventing infection.

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Proliferation (Wound Healing)

Wound healing stage (5 days - 3 weeks) where the wound is rebuilt with granulation tissue.

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Remodeling (Wound Healing)

Wound healing stage (3 weeks - 2 years) where the wound contracts, and the scar shrinks.

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Wound Undermining

Area of tissue loss present under intact skin around wound edges.

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Slough (Wound)

Non-viable tissue composed of dead cells; hinders healing.

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Necrotic Tissue (Wound)

Dead tissue that is no longer viable; prevents healing.

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Wound Dehiscence

Separation or opening of a wound or incision.

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Evisceration

Protrusion of internal organs through a wound.

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Wound Tunneling

A wound that extends deeper into tissue, creating a channel.

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Negative Pressure Wound Therapy (NPWT)

Wound management using negative pressure to remove fluid and stabilize edges.

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Debridement

Removal of dead or damaged tissue from a wound to promote healing.

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Sharp Debridement

Debridement using sharp tool to remove necrotic tissue.

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Enzymatic Debridement

Debridement using topical agents to break down dead tissue.

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Autolytic Debridement

Debridement using occlusive dressings and body's own enzymes.

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Epithelial Wound Bed

Appears pink or pearly white; occurs when the wound is covered by healthy epithelium.

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Granulation Wound Bed

Appears red and moist; healthy tissue formed in remodeling phase.

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Slough (Wound Bed)

Appears yellow, brown, or grey; devitalized tissue.

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Necrotic Wound Bed

Appears hard, dry, and black; dead tissue preventing healing.

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Hyper-granulation

Appears red, uneven, or granular; occurs when tissue is overgrown.

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Serous Exudate

Clear, thin, and watery wound drainage.

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Serosanguineous Exudate

Thin and watery wound drainage with light red or pink hue.

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Sanguineous Exudate

Bright red wound drainage; fresh blood.

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Purulent Exudate

Thick, opaque, and odorous wound drainage; indicates infection.

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Study Notes

Water

  • Facilitates control of body temperature
  • Maintains pH balance
  • Regulates fluid and electrolyte balance
  • Intracellular and extracellular fluids contains water
  • Impacts blood volume
  • Elderly may experience impaired sense of thirst

Vitamins

  • Categorized as fat-soluble or water-soluble

Fat-Soluble Vitamins

  • Stored in the liver and fatty tissue
  • Can accumulate in the body

Water-Soluble Vitamins

  • Need to be replenished regularly

Vitamin A

  • Important for vision
  • Important for infection resistance
  • Important for skin integrity
  • Can be sourced from liver, milk, and dark green leafy vegetables

Vitamin D

  • Helps with bone and tissue formation
  • Can be sourced from sunshine and dairy products

Vitamin E

  • Acts as an antioxidant needed to protect cells
  • Can be sourced from nuts, seeds, and vegetable oil

Vitamin K

  • Essential for clotting and coagulation
  • Can be sourced from dark leafy green vegetables

Vitamin C

  • Helps with collagen synthesis
  • Helps with wound healing
  • Helps with antibodies development
  • Can be sourced from fruits and sweet potatoes

Vitamin B Complex (8 Vitamins)

  • Supports RBC production
  • Supports energy metabolism
  • Supports DNA synthesis
  • Can beb sourced from whole grains, nuts, legumes, and dark leafy green vegetables

Minerals

  • Needed for bone tissue and teeth maintenance
  • Needed for nerve conduction
  • Needed for muscle and blood vessel contraction
  • Sources include dairy, legumes, tomatoes, smoked meat, fruits, fish and dark leafy green vegetables

Carbohydrates

  • Main source of energy
  • Include sugars, starches and fiber
  • When depleted, the body uses protein and stores fat
  • Glycogen is necessary for tissue and brain function
  • Fiber benefits the cardiovascular system and helps with bowel regularity
  • Sources are bread, starchy vegetables, rice, peas and potatoes

Fats

  • Provide production energy
  • Support and insulate organs and nerves
  • Help absorb and transport certain vitamins
  • Contribute to cell membrane structure
  • Sourced from avocados, fish, and oils

Protein

  • Necessary for development
  • Necessary for maintenance
  • Necessary for repair of body tissues
  • Plays a role in the clotting cascade
  • Protein is not stored in the body unlike carbs and fats
  • If necessary, protein can be used for energy
  • Sources are milk, eggs, cheese, poultry, and meat

Lab Values, what they measure, and potential indications

  • Glucose normal range is 70-110
  • Glucose indicates the primary energy source and brain function
  • Hypoglycemia is indicated by low levels of glucose and can cause a medical emergency
  • High levels of glucose indicate hyperglycemia and may cause organ dysfunction
  • Prealbumin normal range is 19.5-35.8
  • Prealbumin indicates a short-term marker for nutrition (protein)
  • Low levels of prealbumin indicate low protein levels
  • High levels of prealbumin indicate high protein levels - changes faster and fluctuates more
  • Albumin normal range is 3.5-5.0
  • Albumin indicates a long-term marker for nutrition (protein)
  • Low levels of albumin indicate low protein levels
  • High levels of albumin indicate high protein levels, does not change as fast
  • Transferrin, when low, indicates malnutrition which causes anemia/iron deficiency
  • Male Hemoglobin normal range is 14-18
  • Female Hemoglobin normal range is 12-16
  • Hemoglobin indicates RBC count and how well oxygen is carried
  • Not carrying oxygen well or low RBCs, refers to hemoglobin
  • High CO2 indicated by hemoglobin determines how well RBCs are carrying oxygen
  • Hematocrit normal range is 35 to 45
  • Hematocrit indicates % of RBCs in plasma
  • Not carrying oxygen well indicates the % of hematocrit
  • High CO2 indicates the % of hematocrit
  • BUN normal range is 8-23
  • BUN indicates metabolic waste products in the blood
  • Fluid overload indicates the metabolic waste product in the blood stream
  • Dehydration is an indication of BUN
  • Creatinine normal range is 0.5-1.2
  • Creatinine indicates kidney function
  • Increased kidney function indicates creatinine
  • Decreased kidney function indicates creatinine determines how well the kidneys are filtering and functioning
  • Lipid profile indicates the cholesterol, LDL, and HDL
  • HDL-good cholesterol protects arteries
  • Heart disease is indicated when there is risk for atherosclerosis due to blood vessels narrowing and hardening

Calcium

  • Normal range is 8.2-10.2
  • Indicates muscle contraction, nerve conduction and bone health
  • Decreased bone density or vitamin D deficiency or brittle bones indicated by calcium levels
  • Overactive parathyroid, kidney disease, or excessive vitamin D indicated by calcium levels

Magnesium

  • Normal range is 1.3-2.0
  • Indicates Muscle contraction and nerve conduction
  • Muscle cramps fatigue or irregular heart rate indicates low magnesium levels
  • Seizures, Kidney failure, Muscle weakness, and cardiac arrest indicated by magnesium levels

Sodium

  • Normal range is 135-145
  • Indicates fluid status, muscle contraction and nerve conduction
  • Muscle cramps, nausea, vomiting, fatigue indicates sodium
  • Dehydration, confusion, or fatigue indicated by sodium levels
  • Hyponutremia indicates sodium levels
  • Hypernatremia indicated by sodium levels

Potassium

  • Normal range is 3.5-5.0
  • Indicates Electrolyte balance
  • Muscle weakness, irregular heart rate, or respiratory failure indicated by potassium levels
  • Kidney disease, Kidney failure, or Seizures are indicated by potassium levels
  • Hyperkalemia is indicated potassium level
  • Hypokalemia indicated by potassium blood levels

Iron

  • Men: normal range is 70-175
  • Female: normal range is 50-170
  • Indicates Hemoglobin production
  • Anemia or low RBC count with not carrying oxygen indicates low iron
  • Iron overload or liver disease indicated by iron levels

Hemoglobin A1c

  • Should be below 5.7%
  • Indicates a 3-month average of blood glucose levels
  • Hypoglycemia is indicated by low hemoglobin A1c levels
  • Hyperglycemia indicated by hemoglobin A1c levels

Stages of Wound Healing

  • Wound healing occurs in three stages: inflammation, proliferation, and remodeling
  • The appearance of the wound will change as the wound heals

Inflammation (2-5 days)

  • Neutrophils and monocytes work to remove debris and prevent infection
  • An increase in these cells will be observed in lab work
  • Signs and symptoms include redness, warmth, pain, and decreased function in the area

Proliferation (5 days-3 weeks)

  • The wound is rebuilt with granulation tissue and collagen to repair the wound
  • A scar is formed

Remodeling (3 weeks-2 years)

  • The wound contracts and the scar shrinks

Factors Affecting Wound Healing

  • Oxygenation and tissue perfusion
  • Diabetes
  • Nutrition
  • Age
  • Infection

Wound Complications

  • Undermining: area of tissue loss present under intact skin usually along the edges of a wound, forming a “lip” around the wound
  • Slough: non-viable tissue, composed of dead cells and an extracellular matrix that appears as a moist, yellow, tan, or white layer on a wound surface hindering healing and increasing the risk of infection
  • Necrotic Tissue: dead tissue that is no longer viable, often appearing as dry, leathery “eschar” or moist, stringy “slough”
  • Dehiscence: the separation or opening of a wound or incision
  • Evisceration: the protrusion of internal organs, especially those in the abdominal cavity, through a wound or incision
  • Tunneling: a wound that extends deeper into the tissue than its surface, creating a channel or passageway, often referred to as a sinus tract, and can be difficult to heal

Wound Management

  • Negative Pressure Wound Therapy (NPWT)/vacuum assisted closure (VAC): uses negative pressure to remove excess wound fluid, stabilize the wound edges, and stimulate granulation tissue
  • Hemovac Drain: soft drain attached to a springlike suction device (closed drain system)
  • Jackson-Pratt Drain (JP drain): soft drain attached to a bulblike suction device (closed drain system)

Debridement

  • May need to occur in wounds that have stalled in healing due to dead tissue

Types of Debridement

  • Sharp: using a sharp instrument (scalpel, curette, or scissors) to remove necrotic tissue, fastest way of removing nonviable tissue and is the method of choice if an underlying infection is suspected or if a large amount of necrotic tissue needs to be removed rapidly
  • Enzymatic: achieved through the application of topical agents containing enzymes that work by breaking down the fibrin, collagen, or elastin present in devitalized tissue, thus allowing for its removal; slower method of debridement than mechanical or sharp, it is selective for nonviable tissue and is quite effective when used appropriately (EX: Santyl, Panafil, and Accuzyme)
  • Autolytic: uses occlusive dressings (such as hydrocolloids and transparent films) as are hydrogels; based on the principle that wounds have an innate ability to clean themselves of debris and necrotic tissue through the action of the body’s own enzymes and phagocytic cells; requires a moist wound environment and the optimization of the other factors important for wound healing in order to be successful; slowest form of debridement and is contraindicated in infected wounds; most comfortable form of debridement for the patient

Wound Assessment

  • -Measurement: Wound measurement provides baseline information while continuous measurement helps to predict healing and aids monitoring of treatment efficacy and evaluation
  • Measure the length "head-to-toe" at the longest point (A)
  • Measure the width side-to-side at the widest point (B) that is perpendicular to the length, forming a "+"
  • Measure the depth (C) at the deepest point of the wound
  • All measures should be in centimeters and use a disposable ruler

Wound Bed

  • Epithelial: Appears pink or pearly white and wrinkles when touched and occurs in the final stage of healing when the wound is covered by healthy epithelium
  • Granulation: Appears red and moist and occurs when healthy tissue is formed in the remodeling phase that is well vascularized and bleeds easily
  • Slough: Appears yellow, brown or grey; slough is devitalized tissue made of dead cells or debris
  • Necrotic: Appears hard, dry, and black; necrotic tissue is dead tissue that prevents wound healing
  • Hyper-granulation: Appears red, uneven, or granular. Occurs in the proliferative phase when tissue is overgrown

Moisture/Exudate

  • Essential part of the healing process
  • Produced by all wounds to maintain a moist environment, cleanse the wound, provide nutrients and white blood cells, as well as promote epithelialization
  • The overall goal of exudate is to effectively donate moisture and contain it within the wound bed
  • Excess exudate in the wound bed leads to maceration and degradation of skin, while too little moisture can result in the wound bed drying out
  • The type of dressing may change multiple times throughout the healing process to maintain an ideal healing environment

Wound Edges

  • The edges of the wound should be showing signs of healing, even if it’s only 1 cm at a time
  • Wound edges that are raised, red, or rolled are not conducive to healing and may need to be debrided

Edges

  • Wound edges are described by their color and if they are raised or rolled for documentation purposes

Odor

  • Wounds should not have a foul odor to them, a foul odor signifies infection
  • An odiferous wound may have associated purulent drainage, but not all the time
  • Odor is assessed after the wound is cleansed
  • Document a 'foul odor' or 'no odor' for documentation purposes

Periwound

  • The outer 1 inch of skin surrounding the wound
  • The peri wound should be pink or appropriate to the ethnicity of the client
  • Document if any edema, redness, or maceration is assessed

Pain

  • Assess pain before, during, and after the dressing change
  • Pre-medicate for long or complex dressing changes
  • Use the numeric scale, Faces scale, or FLACC scale as appropriate

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