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Questions and Answers
Which factor does NOT decrease the synthesis of vitamin D?
Which factor does NOT decrease the synthesis of vitamin D?
Which disease is associated with vitamin D deficiency in children?
Which disease is associated with vitamin D deficiency in children?
What is a potential consequence of vitamin D toxicity?
What is a potential consequence of vitamin D toxicity?
What is the recommended daily intake of vitamin D for individuals aged 71 years and older?
What is the recommended daily intake of vitamin D for individuals aged 71 years and older?
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Which of the following is NOT a function of vitamin D?
Which of the following is NOT a function of vitamin D?
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What is a primary function of Vitamin E?
What is a primary function of Vitamin E?
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Which of the following is a key symptom of Vitamin E deficiency?
Which of the following is a key symptom of Vitamin E deficiency?
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What is the daily recommended amount of Vitamin K for women?
What is the daily recommended amount of Vitamin K for women?
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Which food source is highest in Vitamin E content?
Which food source is highest in Vitamin E content?
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What group of vitamins does Vitamin D belong to?
What group of vitamins does Vitamin D belong to?
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Which of these conditions can lead to Vitamin E deficiency?
Which of these conditions can lead to Vitamin E deficiency?
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What is a common effect of excessive Vitamin E intake?
What is a common effect of excessive Vitamin E intake?
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What is one of the functions of Vitamin C?
What is one of the functions of Vitamin C?
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Which of the following is NOT a sign of Vitamin C deficiency?
Which of the following is NOT a sign of Vitamin C deficiency?
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What is the recommended dietary intake of Vitamin C for men?
What is the recommended dietary intake of Vitamin C for men?
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Which of the following foods is a good source of Vitamin C?
Which of the following foods is a good source of Vitamin C?
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What toxicity symptoms can occur from excessive Vitamin C intake?
What toxicity symptoms can occur from excessive Vitamin C intake?
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Which B vitamin is specifically important for glucose metabolism?
Which B vitamin is specifically important for glucose metabolism?
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What is the upper limit of Vitamin C intake for adults?
What is the upper limit of Vitamin C intake for adults?
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Which deficiency disease is associated with Thiamin (B1) deficiency?
Which deficiency disease is associated with Thiamin (B1) deficiency?
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What is the primary feature that distinguishes fat-soluble vitamins from water-soluble vitamins?
What is the primary feature that distinguishes fat-soluble vitamins from water-soluble vitamins?
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Which of the following vitamins is NOT classified as fat-soluble?
Which of the following vitamins is NOT classified as fat-soluble?
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What is a potential consequence of consuming excessively high doses of water-soluble vitamins?
What is a potential consequence of consuming excessively high doses of water-soluble vitamins?
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Which statement is true regarding the absorption of fat-soluble vitamins?
Which statement is true regarding the absorption of fat-soluble vitamins?
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What are the food sources most likely required for obtaining vitamins?
What are the food sources most likely required for obtaining vitamins?
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Why might fat-soluble vitamins lead to a greater risk of toxicity than water-soluble vitamins?
Why might fat-soluble vitamins lead to a greater risk of toxicity than water-soluble vitamins?
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What is the purpose of vitamins in the body?
What is the purpose of vitamins in the body?
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How often do water-soluble vitamins typically need to be consumed?
How often do water-soluble vitamins typically need to be consumed?
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What is the primary role of vitamin K in the body?
What is the primary role of vitamin K in the body?
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Which of the following is NOT a form of vitamin A found in animal foods?
Which of the following is NOT a form of vitamin A found in animal foods?
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What is one of the signs of vitamin A deficiency?
What is one of the signs of vitamin A deficiency?
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Which vitamin is recognized for its antioxidant properties and protects tissues from oxidative damage?
Which vitamin is recognized for its antioxidant properties and protects tissues from oxidative damage?
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How does the human body convert dietary sources of vitamin A?
How does the human body convert dietary sources of vitamin A?
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What is the recommended dietary intake of active vitamin A for men?
What is the recommended dietary intake of active vitamin A for men?
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Excessive consumption of which food source can potentially lead to vitamin A toxicity?
Excessive consumption of which food source can potentially lead to vitamin A toxicity?
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Which vitamin is primarily responsible for generating pigments necessary for vision?
Which vitamin is primarily responsible for generating pigments necessary for vision?
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Which type of Wernicke Korsakoff syndrome is characterized by muscle wasting?
Which type of Wernicke Korsakoff syndrome is characterized by muscle wasting?
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What are the primary symptoms of riboflavin deficiency?
What are the primary symptoms of riboflavin deficiency?
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Which of the following is considered a key food source of niacin?
Which of the following is considered a key food source of niacin?
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What is a deficiency disease associated with niacin?
What is a deficiency disease associated with niacin?
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What is one role of vitamin B6 in the body?
What is one role of vitamin B6 in the body?
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Which vitamin is known to help develop the brain and nervous system of a fetus?
Which vitamin is known to help develop the brain and nervous system of a fetus?
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Which of the following is NOT a common symptom of Wernicke Korsakoff syndrome?
Which of the following is NOT a common symptom of Wernicke Korsakoff syndrome?
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What is the recommended daily intake of riboflavin for men?
What is the recommended daily intake of riboflavin for men?
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Study Notes
Vitamins Lecture 7
- Vitamins are essential, non-caloric organic nutrients required in small amounts
- Vitamins do not supply energy
- They cannot be synthesized by the body; obtained through diet, rumen bacteria, or sun
- Vitamins are individual units, not linked together like carbohydrates, proteins, and fats
- Required for growth, maintenance, reproduction, and lactation
Learning Objectives
- Identify the meaning of vitamins
- Compare fat-soluble vs. water-soluble vitamins
- Discuss fat-soluble vitamins: roles, food sources, function, deficiency, and toxicity
- Discuss water-soluble vitamins: roles, food sources, function, deficiency, and toxicity
What are Vitamins?
- Vitamins are essential, noncaloric organic nutrients required in small amounts.
- Vitamins do not supply energy.
- They cannot be synthesized by the body.
- They must be obtained from outside sources like diet, rumen bacteria, and the sun.
- Vitamins are individual units; they are not linked together.
- They are needed for growth, maintenance, reproduction, and lactation.
Classification of Vitamins
- Fat-soluble vitamins: A, D, E, and K
- Water-soluble vitamins: C and B complex
Characteristics of Fat- Soluble and Water-Soluble Vitamins
Feature | Fat-Soluble Vitamins | Water-Soluble Vitamins |
---|---|---|
Absorption | Absorbed into lymph and then into the blood. Travel in the blood with protein carriers, stored in the liver or fatty tissues. | Absorbed directly into the blood. Travel freely in watery fluids, most are not stored in the body. |
Transport and storage | Travel in the blood with protein carriers; stored in the liver or fatty tissues. | Travel freely in watery fluids; most are not stored in the body |
Excretion | Not readily excreted; tend to build up in tissues. | Readily excreted in the urine. |
Toxicity | More likely from supplements but rarely from food. | Unlikely but possible with high doses from supplements. |
Requirements | Needed in periodic doses (weeks or months). | Needed in frequent doses (1-3 days). |
Fat-Soluble Vitamins
- Play diverse roles in the body
- Vitamins A and D act as hormones
- Vitamin E protects tissues from destructive oxidative reactions
- Vitamin K is essential for blood clotting and bone health
Vitamin A
- A group of similar compounds called retinoids
- 3 forms: retinol (most active), retinal, and retinoic acid
- About 10% of plant-derived carotenoids (like beta-carotene) are converted into retinoids in the body
- Carotenoids are pigments that give plants their yellow, orange, and red colors
Functions of Vitamin A
- Vision (Retinol generates pigments for the retina, maintains eye coverings and linings)
- Regulation of gene expression (Reproduction)
- Required for cell growth and division (Epithelial cells, bones, and teeth)
- Development of immune cells
- Healthy skin
Vitamin A Recommendations and Sources
- Dietary Reference Intake (DRI) for vitamin A is based on body weight.
- Men need approximately 900 micrograms
- Women need approximately 700 micrograms. Higher during lactation
- Food sources:
- Animal sources (eggs, meat, cheese, milk, liver, kidney)
- Plant sources (carrots, sweet potatoes, pink grapefruit, apricots, broccoli, spinach, pumpkin)
- Human body converts all dietary forms of vitamin A into retinol
Signs of Vitamin A Deficiency
- Night blindness, exophthalmia
- Decreased resistance to infections
- Extremely dry skin, hair, or nails
- Anemia
- Retarded growth in children
Vitamin A Toxicities
- Single large doses of supplements or eating excessive amounts of liver
- Symptoms: dry, itchy skin, headaches, fatigue, hair loss, blurred vision, loss of appetite, swelling of the brain, joint pain, skin discoloration, liver damage, and coma
- Excessive vitamin A during pregnancy can injure the heart, spinal cord, and other tissues, potentially causing birth defects
Vitamin E
- Alpha-tocopherol is the only form recognized to meet human requirements
- Antioxidant
- Stops free radical formation
- Discourages some types of cancer
- Necessary for normal nerve development
- Promotes normal growth and development
- Inhibits blood clotting
- Aids in wound healing
- Boosts the immune system
Vitamin E Recommendations and Sources
- 15 milligrams per day for adults
- Sources: Wheat germ oil, vegetable oils, nuts and seeds, whole grains, egg yolk, and leafy green vegetables
- Vitamin E is easily destroyed by heat
Vitamin E Deficiency
- Insufficient levels are rare, primarily in diets extremely low in fat for years
- High-risk groups: malabsorption disorders (Crohn's disease or cystic fibrosis), premature babies
- Deficiency symptoms: red blood cell breakage, nerve damage, loss of muscle coordination, impaired vision and speech
- Toxicities: more than 1000 milligrams/day can augment the effect of anti-clotting medication.
Vitamin K
- Produced by bacteria in the large intestine
- Function: promotes synthesis of blood clotting and bone formation
- Deficiency symptoms: hemorrhaging, rare in infants after prolonged antibiotic therapy, or patients with decreased bile production
Vitamin K Recommendations and Sources
- Toxicity symptoms are not known if less than 1000 mg/day intake.
- Sources: bacterial synthesis in the digestive tract, milk, leafy green vegetables, cabbage-type vegetables
- For men: 120 micrograms a day
- For women: 90 micrograms a day
Vitamin D
- Synthesized in the body with the help of sunlight
- The skin synthesizes vitamin D when exposed to sunlight
- Vitamin D is not an essential nutrient.
Vitamin D Factors Affecting Synthesis
- Season: Long winters decrease synthesis
- Sunscreen use: Prevents sunlight absorption, decreasing synthesis
- Skin color: Darker skin needs more time for exposure to sunlight, decreased synthesis
- Time of day: Vitamin D3 synthesis increases in the morning
- Age: Older people have decreased synthesis
- Clothing: Wearing clothing that covers the skin decreases synthesis
Vitamin D Function
- Essential for proper utilization of calcium and phosphorus needed to produce healthy bones
- Plays a role in muscle function and the immune system
- Might help prevent colon, prostate and breast cancers
- Might help prevent and treat diabetes, heart disease, high blood pressure, and multiple sclerosis
Vitamin D Deficiency Diseases
- Rickets (Children develop bowed legs, weak, and deformed bones)
- Osteomalacia (Adults, their bones become soft, flexible, weak, and deformed)
- Toxicities symptoms:
- Increase blood calcium
- Calcification of soft tissues (blood vessels, kidneys, heart, lungs, tissues in joints)
- Loss of appetite, nausea, vomiting, frequent urination, fatigue, back pain, and irregular heartbeat
Vitamin D Sources and Recommendations
- Synthesized in the body with the help of sunlight
- Less than 30 minutes of sun exposure to arms and legs increases blood levels of vitamin D3
- Fortified milk, margarine, butter, cereals, beef, egg yolk, liver, fatty fish
- 1 to 70 years old need 15 micrograms daily; 71 and older need 20 micrograms per day
Water-soluble Vitamins
- Water-soluble vitamins are absorbed directly into the bloodstream, where they function.
- Most aren't stored, but are readily excreted via the urine.
Vitamin C
- Function: protects the body from free radicals, forms connective tissues (collagen), aids in wound healing, aids in iron absorption, boosts gums, helps fight infections, aids in preventing heart disease
- Deficiency signs: Scurvy (bleeding gums, loosened teeth, swollen ankles and wrists, and tiny red spots in skin), fatigue and joint pain, reduced resistance to colds and infections, slow healing of wounds and fractured bones, anemia.
- Toxicity: over 1000 mg/day; symptoms: nausea, abdominal cramps, diarrhea, headache, fatigue, insomnia, rashes, urinary tract problems, kidney stones
- Sources: citrus fruits (oranges, grapefruits, lemons, limes); cabbage-type vegetables, dark green vegetables (broccoli); strawberries; berries; melons; papayas; mangoes; potatoes; tomatoes; guava
- Recommended Dietary Intake for adults: 90 mg per day (men), 75 mg per day (women), smokers + 35mg per day
B Complex
- Thiamin B1, Riboflavin B2, Niacin B3, Folate B9, B6, B12, Biotin B7, and Pantothenic acid
- Functions: aid in the metabolism of carbohydrates, lipids, and amino acids; part of coenzymes; and activate enzymes.
- Some detailed notes on specific B vitamins follows below
Thiamin B1
- Function: Important in glucose metabolism; cofactor for enzymes breaking down glucose for energy production. Plays a role in neurotransmitter synthesis; required for RNA, DNA, and ATP synthesis
- Food sources: whole-grain, fortified, or enriched grain products; moderate amounts in all nutritious food
- Toxicity: None reported
Riboflavin B2
- Function: Essential component of flavoproteins (coenzymes) involved in carbohydrate, lipid, and protein metabolism; gives a bright yellow color to riboflavin.
- Food sources: Milk and dairy products (yogurt, cheese), enriched or whole grains, liver
Niacin B3
- Function: Like thiamin and riboflavin, participates in energy metabolism of every cell.
- Amino acid tryptophan is abundant in protein. Converted into niacin in the body.
- Deficiency disease: Pellagra (dermatitis, diarrhea, dementia, and death)
- Food sources: foods high in vitamin B3 niacin (broccoli, peanuts, chicken, mushrooms, bell peppers, kidney beans)
Vitamin B6 (Pyridoxine)
- Function: Part of coenzyme needed in amino acid and fatty acid metabolism. Essential for converting methionine into cysteine and tryptophan into niacin and serotonin. Helps make hemoglobin, releases stored glucose, and develops fetal brain/nervous system.
- Deficiency symptoms: Weakness, depression, confusion, irritability, convulsions, insomnia, and greasy dermatitis (the skin is greasy and flaky).
- Food sources: Meat, fish, poultry (protein-rich foods), starchy vegetables, fruits, and leafy green vegetables
Folate B9 (Folic Acid)
- Function: Required for making RNA and DNA, and works with B12 to form hemoglobin, Essential for amino acid methionine synthesis
- Deficiency: anemia (large-cell type), smooth red tongue, mental confusion, weakness fatigue, irritability, headache; helps prevent neural tube defects like spina bifida
- Food sources: fortified grains, leafy green vegetables, legumes, seeds, liver
Vitamin B12 (Cobalamin)
- Function: Part of coenzymes used in new cell synthesis; helps maintain nerve cells, helps break down fatty acids, essential for hemoglobin synthesis, converts folate to active form.
- Deficiency disease: pernicious anemia (large and immature red blood cells), anemia, fatigue, paralysis/nerve damage in the fetus
- Food sources: animal products (meat, poultry, fish, shellfish, milk, cheese, eggs), fortified cereals
- Toxicity: None reported
Deficiency Diseases: Beriberi & Wernicke Korsakoff syndrome
- Beriberi: two types (wet and dry), causes muscle wasting, edema, fatigue, confusion, movement impairment, pain in lower extremities. Swelling, and heart failure.
- Wernicke Korsakoff syndrome: confusion, loss of coordination, vision changes, hallucinations, and may lead to coma and death. Specific to alcoholics due to high alcohol intake.
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Test your knowledge on vitamins, their functions, recommended intakes, and deficiency diseases with this engaging quiz. Explore key facts about Vitamin D, E, K, and C to enhance your understanding of nutrition and health.