Virus Transmission and Inactivation Quiz
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Questions and Answers

What is the primary function of the viral capsid?

  • To aid in the delivery of nucleic acid to the host cell for infection (correct)
  • To trigger an immune response in the host
  • To replicate within the living cells of a host
  • To produce antibodies to fight the virus

What is the difference between naked and enveloped virus release?

  • Enveloped viruses are released by cell lysis
  • Enveloped viruses are more likely to cause cell damage (correct)
  • Naked viruses are usually released by exocytosis
  • Naked viruses leave the host cell intact

What is the function of interferon α in combating viral infection?

  • Destroying infected cells
  • Halting protein synthesis in infected cells (correct)
  • Producing antibodies to free the virus
  • Inducing cell-mediated immune response

How are primary histocompatibility complex (MHC) class I molecules involved in combating viral infection?

<p>Presenting viral antigens to T lymphocytes to induce a cell-mediated immune response (A)</p> Signup and view all the answers

What is the significance of a virus having an envelope?

<p>It impacts how the virus replicates and infects (B)</p> Signup and view all the answers

What is the primary role of natural killer (NK) cells during viral infection?

<p>To destroy infected cells (A)</p> Signup and view all the answers

What is the main purpose of spike glycoproteins and fusion proteins in enveloped viruses?

<p>To assist with viral attachment and entry into host cells (B)</p> Signup and view all the answers

How do viruses differ from bacteria in terms of replication?

<p>Viruses cannot replicate on their own, while bacteria can divide on their own (A)</p> Signup and view all the answers

What is the main difference between viruses and bacteria in terms of metabolic activity?

<p>Viruses are metabolically inert, while bacteria can make energy and encoded proteins (D)</p> Signup and view all the answers

How many families of human pathogens are contained within RNA viruses?

<p>16 (B)</p> Signup and view all the answers

What is a virion?

<p>A single, infective, complete, and mature viral particle that can deliver the viral genome and lead to a productive infection in an appropriate host cell (A)</p> Signup and view all the answers

What are the main structures of a virus?

<p>Capsid, Envelope, Genome (D)</p> Signup and view all the answers

What is the primary aim of antiviral medications?

<p>To prevent the virus from completing its metabolic process for self-replication (A)</p> Signup and view all the answers

What is the primary function of Palivizumab?

<p>Targeting respiratory syncytial virus (RSV) to prevent fusion to the host cell membrane (A)</p> Signup and view all the answers

What are the side effects of Amantadine?

<p>Nausea, anorexia, nervousness, insomnia, seizures, and livedo reticularis (reddish-blue mottling of the skin) (C)</p> Signup and view all the answers

What is the additional potential use for Amantadine?

<p>Treatment of Parkinson's Disease (B)</p> Signup and view all the answers

How does Acyclovir exert its antiviral activity?

<p>By acting as a substrate and inhibitor of viral DNA-polymerase (C)</p> Signup and view all the answers

What is the function of Interferon-α?

<p>Halting protein synthesis in uninfected cells and helping mount an immune response (A)</p> Signup and view all the answers

What type of viruses are more likely to be transmitted via direct host-to-host contact or inhalation?

<p>Enveloped viruses (C)</p> Signup and view all the answers

What is the main advantage of having an envelope for a virus?

<p>Enveloped viruses have more surface proteins, enhancing their ability to infect and replicate (B)</p> Signup and view all the answers

What determines host range and specificity in viruses?

<p>Cell susceptibility and permissiveness (C)</p> Signup and view all the answers

What are the six steps of the viral replication cycle?

<p>Attachment, uncoating, replication, assembly, release, and maturation (C)</p> Signup and view all the answers

What is the primary target of an effective neutralizing antibody?

<p>Membrane glycoprotein of an enveloped virion (A)</p> Signup and view all the answers

What is the term for the nucleic acid that makes up a viral genome?

<p>DNA or RNA (A)</p> Signup and view all the answers

What is the primary method that viruses use to replicate within host cells?

<p>By using the host cell's machinery and building blocks (A)</p> Signup and view all the answers

How do naked viruses penetrate the host cell?

<p>By creating a new opening in the host cell membrane (D)</p> Signup and view all the answers

What determines which cells/tissues/organisms will be affected by a virus?

<p>Virus cell susceptibility and host cell permissiveness (D)</p> Signup and view all the answers

What is the difference between viral attachment and viral adhesion?

<p>Attachment refers to binding of the virion, adhesion refers to the penetration of the virus into the host cell (D)</p> Signup and view all the answers

How does a virus initially bind to a cell receptor?

<p>Through electrostatic forces, followed by other short-range forces (A)</p> Signup and view all the answers

What is the role of neutralizing antibodies in viral entry?

<p>To block viral penetration into host cells (C)</p> Signup and view all the answers

What is the function of the nuclear pore complex?

<p>Facilitate entry of viruses into the nucleus (A)</p> Signup and view all the answers

What are karyopherins responsible for?

<p>Allowing viruses to infect non-dividing, terminally differentiated cells (C)</p> Signup and view all the answers

Which cellular process includes genome duplication, gene transcription, and protein translation?

<p>Cell division (D)</p> Signup and view all the answers

Where does viral assembly occur?

<p>Different cellular compartments (B)</p> Signup and view all the answers

What is limited by the size of the capsid?

<p>Packaging of viral genetic material (B)</p> Signup and view all the answers

What happens during envelopment in enveloped viruses?

<p>They acquire an external membrane layer derived from a host organelle or the plasma membrane (A)</p> Signup and view all the answers

What is the role of the nucleic acid in a virus?

<p>Contains genetic instructions for replication and host cell infection (C)</p> Signup and view all the answers

Which cellular component is involved in allowing viruses to infect non-dividing, terminally differentiated cells?

<p>Karyopherins (A)</p> Signup and view all the answers

What does viral packaging involve?

<p>Incorporation of viral genetic material into the capsid (D)</p> Signup and view all the answers

Where do enveloped viruses acquire an external membrane layer from?

<p>Host organelle or the plasma membrane (A)</p> Signup and view all the answers

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