Virus Structure and Classification Quiz
48 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What are the main structural components of a virus?

  • Deoxyribonucleic acid and a carbohydrate layer
  • Ribonucleic acid and a lipid bilayer
  • A genome and a protein-containing structure (correct)
  • A protein coat and a lipid envelope

How do viruses differ in pathogenicity?

  • Pathogenicity is determined by the host organism rather than the virus
  • They all produce the same clinical pathologies
  • They can produce distinct clinical pathologies based on structural characteristics (correct)
  • All viruses have the same structural components which leads to similar pathologies

What is the typical size range of viruses compared to the cells they infect?

  • Approximately 100- to 1000-fold smaller than the cells (correct)
  • Identical in size to the cells they infect
  • Larger than cells by a factor of 10
  • Similar in size to small bacterial cells

Which of the following is NOT a characteristic used to define virus families?

<p>Method of energy production (C)</p> Signup and view all the answers

What is a virion?

<p>A virus particle that combines structural elements (D)</p> Signup and view all the answers

What is the diameter range of the smallest and largest human viruses?

<p>20 nm to 300 nm (C)</p> Signup and view all the answers

What distinguishes a virus from a bacterial cell?

<p>Viruses are smaller and pass-through filters designed for bacteria (A)</p> Signup and view all the answers

Which type of viral capsid symmetry might a virus exhibit?

<p>Helical or icosahedral (D)</p> Signup and view all the answers

What is the primary characteristic that distinguishes Hepadnaviruses from other virus families?

<p>They have an envelope that covers an icosahedral capsid. (C)</p> Signup and view all the answers

Which type of virus is known for causing latent infections?

<p>Herpesviruses (C)</p> Signup and view all the answers

Which of the following viruses is classified as a Picornavirus?

<p>Coxsackievirus (B)</p> Signup and view all the answers

What is a distinguishing feature of Poxviruses?

<p>They have bricklike shapes and cause skin lesions known as 'pocks'. (A)</p> Signup and view all the answers

Which virus family is associated with respiratory tract disease and various infections?

<p>Adenoviruses (A)</p> Signup and view all the answers

What is the diameter range of Hepadnaviruses?

<p>42 nm (B)</p> Signup and view all the answers

Which characteristic describes Caliciviruses?

<p>They are naked viruses with positive-polarity RNA. (C)</p> Signup and view all the answers

How many antigenic types are associated with Adenoviruses?

<p>Over 40 (D)</p> Signup and view all the answers

What differentiates the genera and species within a virus family?

<p>Host range and serologic reactions (B)</p> Signup and view all the answers

Which of the following best describes the composition of helical capsids?

<p>Made up of one type of polypeptide that assembles into a rod-shaped structure (D)</p> Signup and view all the answers

What is true about positive-strand RNA viruses?

<p>They are of messenger RNA sense and can be used for protein synthesis (D)</p> Signup and view all the answers

What is the characteristic structure of reoviruses?

<p>Naked viruses with two icosahedral capsid coats (A)</p> Signup and view all the answers

Which group does the rubella virus belong to?

<p>Togaviruses (C)</p> Signup and view all the answers

Which capsid symmetry involves multiple types of polypeptides grouped into capsomers?

<p>Icosahedral symmetry (A)</p> Signup and view all the answers

Which virus is primarily responsible for diarrhea in infants?

<p>Rotavirus (B)</p> Signup and view all the answers

In terms of viral genomes, what distinguishes negative polarity RNA?

<p>It is complementary to the messenger RNA sense (D)</p> Signup and view all the answers

What is the basic structural unit of helical capsids called?

<p>Protomer (B)</p> Signup and view all the answers

What type of RNA does the hepatitis E virus possess?

<p>Single-stranded positive-polarity RNA (A)</p> Signup and view all the answers

Which group contains human immunodeficiency virus (HIV)?

<p>Retroviruses (B)</p> Signup and view all the answers

What role does the nucleocapsid play in viral structure?

<p>It contains the viral nucleic acid and protomers (C)</p> Signup and view all the answers

Which virus is known as the main pathogen in orthomyxoviruses?

<p>Influenza virus (B)</p> Signup and view all the answers

What type of genome is most commonly found in nature among viruses?

<p>ssRNA and dsDNA (C)</p> Signup and view all the answers

What distinctive feature classifies paramyxoviruses?

<p>Enveloped with helical nucleocapsid (C)</p> Signup and view all the answers

Which of the following statements is true about flaviviruses?

<p>They include the hepatitis C virus (C)</p> Signup and view all the answers

What is the primary reservoir for the MERS coronavirus?

<p>Bats (C)</p> Signup and view all the answers

What was the main mode of transmission for MERS to humans?

<p>Close contact with camels (D)</p> Signup and view all the answers

During which month and year was COVID-19 declared a pandemic by WHO?

<p>March 2020 (D)</p> Signup and view all the answers

Which of the following symptoms is NOT commonly associated with COVID-19?

<p>Vision problems (B)</p> Signup and view all the answers

What percentage of people infected with COVID-19 generally recover without special treatment?

<p>80% (B)</p> Signup and view all the answers

What is a common characteristic of patients who tend to develop severe illness from COVID-19?

<p>Older age (A)</p> Signup and view all the answers

What is the incubation period for COVID-19 as mentioned in the content?

<p>1-14 days (C)</p> Signup and view all the answers

Which type of coronavirus is associated with the disease recognized in 2019?

<p>SARS-CoV-2 (A)</p> Signup and view all the answers

Which of the following viruses is NOT classified as a rhabdovirus?

<p>Human immunodeficiency virus (HIV) (D)</p> Signup and view all the answers

What type of RNA do filoviruses contain?

<p>Single-stranded, linear, nonsegmented, negative-polarity RNA (A)</p> Signup and view all the answers

What is the main transmission method for SARS?

<p>Airborne transmission via droplets (A)</p> Signup and view all the answers

Which statement correctly describes coronaviruses?

<p>They are responsible for diseases like COVID-19 and the common cold. (C)</p> Signup and view all the answers

What year did the severe acute respiratory syndrome (SARS) outbreak begin?

<p>2002 (D)</p> Signup and view all the answers

What is the primary natural reservoir for CoV-SARS?

<p>Horseshoe bat (B)</p> Signup and view all the answers

Which coronavirus is known as SARS-CoV-2?

<p>The virus responsible for COVID-19 (C)</p> Signup and view all the answers

Filoviruses are characterized by their:

<p>Pleomorphic and long filamentous shapes (B)</p> Signup and view all the answers

Flashcards

What is a virus?

A virus is a tiny infectious agent that can only replicate inside a living cell. It's made up of two main parts: a core of genetic material (DNA or RNA) and a protective protein coat called a capsid.

What is a virion?

A virion is a complete virus particle, meaning it has all the parts needed to infect a host cell. This includes the genetic material (DNA or RNA) and its protective protein coat (capsid).

How are viruses classified?

Viruses are divided into families and sometimes subfamilies based on their characteristics, like the type of genetic material they have (DNA or RNA), how they replicate, their shape, and whether they have an outer membrane.

How small are viruses?

Viruses are much smaller than the cells they infect. They can't be seen with a regular microscope and can even pass through filters designed to trap bacteria.

Signup and view all the flashcards

What is a viral envelope?

The presence or absence of an envelope (a lipid bilayer with proteins) is a key difference between virus groups. Some viruses have an envelope, while others don't.

Signup and view all the flashcards

What is a viral genome?

The viral genome is the genetic material (DNA or RNA) that carries the instructions for how to replicate the virus. It's like a blueprint for creating more viruses.

Signup and view all the flashcards

What is a viral capsid?

The capsid is the protein coat that surrounds the viral genome, protecting it and helping it attach to host cells. It's like a shield.

Signup and view all the flashcards

How do viruses replicate?

Viruses do not have their own machinery for replication. To multiply, they have to invade a host cell and use the host's cellular machinery to make copies of themselves.

Signup and view all the flashcards

Capsid

The protein shell that encloses the genetic material (genome) of a virus.

Signup and view all the flashcards

Helical Capsid

A rod-shaped or coiled structure formed by repeating units of a single protein type.

Signup and view all the flashcards

Icosahedral Capsid

A spherical or symmetrical structure formed by multiple protein sub-units (capsomers).

Signup and view all the flashcards

Genome

A virus's genetic material, which can be RNA or DNA.

Signup and view all the flashcards

Single-stranded vs. Double-stranded Genome

The genetic material of a virus is either single-stranded (ss) or double-stranded (ds).

Signup and view all the flashcards

Positive-Strand RNA

A type of RNA genome that can be directly translated into proteins.

Signup and view all the flashcards

Negative-Strand RNA

A type of RNA genome that is complementary to messenger RNA and cannot be directly translated.

Signup and view all the flashcards

Protomer

The basic unit of protein that forms part of a helical capsid.

Signup and view all the flashcards

What are Reoviruses?

These are naked viruses with two icosahedral capsid coats and 10 segments of double-stranded linear RNA. They were originally found in the respiratory and enteric tracts, but not associated with any human disease. The main human pathogen is rotavirus, which causes diarrhea in infants.

Signup and view all the flashcards

What are Flaviviruses?

These are enveloped viruses that have a single-stranded, linear, nonsegmented, positive-polarity RNA genome and an icosahedral capsid. They are known for causing diseases like hepatitis C, yellow fever, dengue fever, West Nile virus, and encephalitis.

Signup and view all the flashcards

What are Togaviruses?

They are enveloped viruses with an icosahedral capsid and single-stranded, linear, nonsegmented, positive-polarity RNA. They include two main groups, alphaviruses and rubiviruses, responsible for encephalitis and rubella respectively.

Signup and view all the flashcards

What are Retroviruses?

These are enveloped viruses with an icosahedral capsid and two identical strands of single-stranded, linear, positive-polarity RNA. They are known for their unique reverse transcription process, where RNA is converted to DNA. They include oncoviruses like the human T-cell leukemia virus (HTLV) and lentiviruses like HIV.

Signup and view all the flashcards

What are Orthomyxoviruses?

These viruses are enveloped, with a helical nucleocapsid and eight segments of linear, single-stranded, negative-polarity RNA. They have an affinity for mucins and include the influenza virus.

Signup and view all the flashcards

What are Paramyxoviruses?

They are enveloped viruses with a helical nucleocapsid and single-stranded, linear, nonsegmented, negative-polarity RNA. These viruses are very different from orthomyxoviruses despite the similarities in their names. They are responsible for diseases like measles and mumps.

Signup and view all the flashcards

What are adenoviruses?

These are naked icosahedral viruses with double-stranded linear DNA. They cause various infections like pharyngitis and respiratory tract disease.

Signup and view all the flashcards

What are Picornaviruses?

These are small RNA viruses with a naked icosahedral capsid and nonsegmented, positive-polarity RNA. They cause infections like polio, coxsackievirus, and hepatitis A.

Signup and view all the flashcards

What are Hepadnaviruses?

These are double-shelled viruses with an icosahedral capsid covered by an envelope. Their DNA is a double-stranded circle with unusual characteristics.

Signup and view all the flashcards

What are Herpesviruses?

These are enveloped viruses with an icosahedral nucleocapsid and double-stranded linear DNA. They are known for causing latent infections.

Signup and view all the flashcards

What are Poxviruses?

These are the largest viruses with a brick-like shape, an envelope, and complex capsid symmetry. They cause skin lesions called 'pocks'.

Signup and view all the flashcards

What are Caliciviruses?

These are naked viruses with an icosahedral capsid. They possess single-stranded, linear, nonsegmented, positive-polarity RNA.

Signup and view all the flashcards

Name the five important human herpesviruses.

These are enveloped viruses with an icosahedral nucleocapsid and double-stranded linear DNA. The five important human pathogens are Herpes Simplex Virus types 1 and 2, Varicella-zoster Virus, Cytomegalovirus, and Epstein-Barr Virus.

Signup and view all the flashcards

How can RNA viruses be classified based on their structure?

The three naked icosahedral virus families are followed by three enveloped icosahedral viruses. The remaining eight families are enveloped helical viruses with single-stranded linear or circular RNA.

Signup and view all the flashcards

What are Rhabdoviruses?

Bullet-shaped enveloped viruses with a helical nucleocapsid and a single-stranded, linear, nonsegmented, negative-polarity RNA. The term "rhabdo" refers to the bullet shape.

Signup and view all the flashcards

What are Filoviruses?

Enveloped viruses with a helical nucleocapsid and single-stranded, linear, nonsegmented, negative-polarity RNA. Known for their long filaments that are 80 nm in diameter but can be thousands of nanometers long. The term "filo" means "thread" and refers to these filaments.

Signup and view all the flashcards

What are Coronaviruses?

Enveloped viruses with a helical nucleocapsid and a single-stranded, linear, nonsegmented, positive-polarity RNA. The term "corona" refers to the halo of spikes protruding from the envelope.

Signup and view all the flashcards

What is COVID-19?

A respiratory illness caused by a virus in the coronavirus family. This virus is called SARS-CoV-2.

Signup and view all the flashcards

What is SARS? (Severe Acute Respiratory Syndrome)

A severe respiratory syndrome caused by a specific type of coronavirus. Emerged in 2002 in China and spread rapidly to other countries, affecting hospital personnel.

Signup and view all the flashcards

What is MERS? (Middle East Respiratory Syndrome)

A serious respiratory illness caused by a specific type of coronavirus, emerged in 2012, and initially affected the Middle East.

Signup and view all the flashcards

What is the only human pathogen in the Rhabdovirus family?

Rabies virus is the only human pathogen in this family. Spread through animal bites and can cause fatal encephalitis.

Signup and view all the flashcards

What are the two human pathogens in the Filovirus family?

Ebola virus and Marburg virus are both human pathogens in this family. They cause severe hemorrhagic fevers.

Signup and view all the flashcards

What is MERS?

Middle East Respiratory Syndrome (MERS) is a severe respiratory illness caused by a coronavirus, MERS-CoV. It was initially detected in Saudi Arabia in 2012 and has since spread to other countries.

Signup and view all the flashcards

What is the origin of MERS-CoV?

MERS-CoV is a coronavirus closely related to a bat coronavirus. It's thought that bats are the natural reservoir for this virus.

Signup and view all the flashcards

How is MERS-CoV transmitted to humans?

Camel contact is the most likely way humans get infected with MERS-CoV. Although person-to-person transmission is possible, it's less common and usually occurs in healthcare settings with weak infection control measures.

Signup and view all the flashcards

What is the incubation period of COVID-19?

The SARS-CoV-2 virus has an incubation period of 1 to 14 days, meaning it takes that long for symptoms to appear after infection. On average, symptoms develop within 6 days.

Signup and view all the flashcards

What are the common symptoms of COVID-19?

The most common COVID-19 symptoms are fever, tiredness, and dry cough. Other symptoms might include body aches, nasal congestion, runny nose, sore throat, or diarrhea. However, some people have no symptoms at all.

Signup and view all the flashcards

Who is at higher risk for severe COVID-19 symptoms?

Around 16% of people with COVID-19 develop serious illness marked by difficulty breathing. Older adults and individuals with underlying medical conditions like high blood pressure, heart problems, or diabetes are at a higher risk for severe complications.

Signup and view all the flashcards

What should you do if you suspect you have COVID-19?

If you experience fever, cough, and difficulty breathing, it's important to seek medical attention. This can help prevent the disease from becoming more severe.

Signup and view all the flashcards

Study Notes

Medical Important Viruses

  • Viruses are infectious agents composed minimally of a genome (RNA or DNA, but not both) and a protein capsid for protection.
  • Some viruses have additional features like an envelope, a lipid bilayer with proteins.
  • A complete virus particle is called a virion.
  • Viruses replicate inside host cells.
  • Viral pathogenicity varies greatly, even within a related virus family.
  • Viruses have different sizes and structures that define viral families, genera, and species.

Virus Structure

  • Viruses are significantly smaller than host cells, ranging from 20 nm to 300 nm.
  • The small size allows them to pass through filters designed to trap bacteria. This lack of a cell wall is a distinguishing feature.
  • Viruses can be categorized as naked (no envelope) or enveloped (with an envelope).

Virus Classification

  • Viruses are classified into groups based on their genome type (DNA or RNA, single-stranded or double-stranded), genome symmetry (helical or icosahedral), and presence of an envelope.
  • The Baltimore classification further categorizes viruses based on the way they produce mRNA.

Virus Replication

  • Virus replication involves a series of steps including attachment to a host cell, penetration, uncoating, gene expression and replication, assembly, and release of progeny virions.
  • Not all steps are the same for every virus.
  • The individual steps in the viral replication cycle vary depending on the type of virus.

Viral Capsid Symmetry

  • The protein shell (capsid) enclosing the viral genome can be either helical (rod-shaped) or icosahedral (spherical).
  • This capsid structure is constructed from multiple copies of a single or a few different polypeptides.

Viral Envelopes

  • An envelope is a lipid bilayer membrane enclosing some viruses.
  • It is derived from the host cell membrane and contains viral proteins, providing virus-specific antigenicity.
  • Viruses without envelopes are called naked viruses.

Viral Genomes

  • Viral genomes can be DNA or RNA, single-stranded or double-stranded.
  • The genome type is a major factor in virus classification.
  • Viral genomes can have positive or negative polarity regarding viral direction and function within mRNA production.

Types of Viruses and Diseases

  • Each type of virus causes specific diseases.
  • For example, herpesviruses cause herpes, poxviruses cause smallpox.
  • Various families are studied: Adenovirus, Papovavirus, Hepadnavirus, Retrovirus etc.

Molecular Tests

  • Diagnostic tests include tests using nucleic acid or antibody detection to understand viral presence/activity, exposure, etc.

Covid-19

  • Covid-19 is a disease caused by SARS-CoV-2.
  • It displayed various symptoms, such as fever and dry cough.
  • The virus replicated in a manner to produce progeny virions, infect respiratory tracts, and enter the blood stream.
  • Different types of vaccines were developed based on mRNA, inactivated viruses, viral vector, or protein-based platforms.
  • There are several variants of the virus, including Alpha, Beta, Gamma, Delta, and Omicron.
  • Prevention involves handwashing, avoiding contact with sick people, wearing a mask, and avoiding crowded places.

Summary

  • Viruses are classified based on their genome type, symmetry, and presence/absence of an envelope.
  • The methods to detect and control viruses involve molecular and immunological approaches, including antibody and PCR tests.
  • The various types of viruses and diseases they cause have been studied.
  • The COVID-19 pandemic highlighted the role of viruses and the need for preventive measures.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

Medical Important Viruses PDF

Description

Test your knowledge on the structural components of viruses and their classification! This quiz covers various aspects such as viral size, pathogenicity, and distinguishing features of different virus families. How well do you understand the complexity of viruses?

More Like This

Medical Important Viruses
48 questions

Medical Important Viruses

RetractableNephrite6474 avatar
RetractableNephrite6474
Virus Structure and Classification Quiz
71 questions
Use Quizgecko on...
Browser
Browser