Podcast
Questions and Answers
What are the main structural components of a virus?
What are the main structural components of a virus?
- Deoxyribonucleic acid and a carbohydrate layer
- Ribonucleic acid and a lipid bilayer
- A genome and a protein-containing structure (correct)
- A protein coat and a lipid envelope
How do viruses differ in pathogenicity?
How do viruses differ in pathogenicity?
- Pathogenicity is determined by the host organism rather than the virus
- They all produce the same clinical pathologies
- They can produce distinct clinical pathologies based on structural characteristics (correct)
- All viruses have the same structural components which leads to similar pathologies
What is the typical size range of viruses compared to the cells they infect?
What is the typical size range of viruses compared to the cells they infect?
- Approximately 100- to 1000-fold smaller than the cells (correct)
- Identical in size to the cells they infect
- Larger than cells by a factor of 10
- Similar in size to small bacterial cells
Which of the following is NOT a characteristic used to define virus families?
Which of the following is NOT a characteristic used to define virus families?
What is a virion?
What is a virion?
What is the diameter range of the smallest and largest human viruses?
What is the diameter range of the smallest and largest human viruses?
What distinguishes a virus from a bacterial cell?
What distinguishes a virus from a bacterial cell?
Which type of viral capsid symmetry might a virus exhibit?
Which type of viral capsid symmetry might a virus exhibit?
What is the primary characteristic that distinguishes Hepadnaviruses from other virus families?
What is the primary characteristic that distinguishes Hepadnaviruses from other virus families?
Which type of virus is known for causing latent infections?
Which type of virus is known for causing latent infections?
Which of the following viruses is classified as a Picornavirus?
Which of the following viruses is classified as a Picornavirus?
What is a distinguishing feature of Poxviruses?
What is a distinguishing feature of Poxviruses?
Which virus family is associated with respiratory tract disease and various infections?
Which virus family is associated with respiratory tract disease and various infections?
What is the diameter range of Hepadnaviruses?
What is the diameter range of Hepadnaviruses?
Which characteristic describes Caliciviruses?
Which characteristic describes Caliciviruses?
How many antigenic types are associated with Adenoviruses?
How many antigenic types are associated with Adenoviruses?
What differentiates the genera and species within a virus family?
What differentiates the genera and species within a virus family?
Which of the following best describes the composition of helical capsids?
Which of the following best describes the composition of helical capsids?
What is true about positive-strand RNA viruses?
What is true about positive-strand RNA viruses?
What is the characteristic structure of reoviruses?
What is the characteristic structure of reoviruses?
Which group does the rubella virus belong to?
Which group does the rubella virus belong to?
Which capsid symmetry involves multiple types of polypeptides grouped into capsomers?
Which capsid symmetry involves multiple types of polypeptides grouped into capsomers?
Which virus is primarily responsible for diarrhea in infants?
Which virus is primarily responsible for diarrhea in infants?
In terms of viral genomes, what distinguishes negative polarity RNA?
In terms of viral genomes, what distinguishes negative polarity RNA?
What is the basic structural unit of helical capsids called?
What is the basic structural unit of helical capsids called?
What type of RNA does the hepatitis E virus possess?
What type of RNA does the hepatitis E virus possess?
Which group contains human immunodeficiency virus (HIV)?
Which group contains human immunodeficiency virus (HIV)?
What role does the nucleocapsid play in viral structure?
What role does the nucleocapsid play in viral structure?
Which virus is known as the main pathogen in orthomyxoviruses?
Which virus is known as the main pathogen in orthomyxoviruses?
What type of genome is most commonly found in nature among viruses?
What type of genome is most commonly found in nature among viruses?
What distinctive feature classifies paramyxoviruses?
What distinctive feature classifies paramyxoviruses?
Which of the following statements is true about flaviviruses?
Which of the following statements is true about flaviviruses?
What is the primary reservoir for the MERS coronavirus?
What is the primary reservoir for the MERS coronavirus?
What was the main mode of transmission for MERS to humans?
What was the main mode of transmission for MERS to humans?
During which month and year was COVID-19 declared a pandemic by WHO?
During which month and year was COVID-19 declared a pandemic by WHO?
Which of the following symptoms is NOT commonly associated with COVID-19?
Which of the following symptoms is NOT commonly associated with COVID-19?
What percentage of people infected with COVID-19 generally recover without special treatment?
What percentage of people infected with COVID-19 generally recover without special treatment?
What is a common characteristic of patients who tend to develop severe illness from COVID-19?
What is a common characteristic of patients who tend to develop severe illness from COVID-19?
What is the incubation period for COVID-19 as mentioned in the content?
What is the incubation period for COVID-19 as mentioned in the content?
Which type of coronavirus is associated with the disease recognized in 2019?
Which type of coronavirus is associated with the disease recognized in 2019?
Which of the following viruses is NOT classified as a rhabdovirus?
Which of the following viruses is NOT classified as a rhabdovirus?
What type of RNA do filoviruses contain?
What type of RNA do filoviruses contain?
What is the main transmission method for SARS?
What is the main transmission method for SARS?
Which statement correctly describes coronaviruses?
Which statement correctly describes coronaviruses?
What year did the severe acute respiratory syndrome (SARS) outbreak begin?
What year did the severe acute respiratory syndrome (SARS) outbreak begin?
What is the primary natural reservoir for CoV-SARS?
What is the primary natural reservoir for CoV-SARS?
Which coronavirus is known as SARS-CoV-2?
Which coronavirus is known as SARS-CoV-2?
Filoviruses are characterized by their:
Filoviruses are characterized by their:
Flashcards
What is a virus?
What is a virus?
A virus is a tiny infectious agent that can only replicate inside a living cell. It's made up of two main parts: a core of genetic material (DNA or RNA) and a protective protein coat called a capsid.
What is a virion?
What is a virion?
A virion is a complete virus particle, meaning it has all the parts needed to infect a host cell. This includes the genetic material (DNA or RNA) and its protective protein coat (capsid).
How are viruses classified?
How are viruses classified?
Viruses are divided into families and sometimes subfamilies based on their characteristics, like the type of genetic material they have (DNA or RNA), how they replicate, their shape, and whether they have an outer membrane.
How small are viruses?
How small are viruses?
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What is a viral envelope?
What is a viral envelope?
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What is a viral genome?
What is a viral genome?
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What is a viral capsid?
What is a viral capsid?
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How do viruses replicate?
How do viruses replicate?
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Capsid
Capsid
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Helical Capsid
Helical Capsid
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Icosahedral Capsid
Icosahedral Capsid
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Genome
Genome
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Single-stranded vs. Double-stranded Genome
Single-stranded vs. Double-stranded Genome
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Positive-Strand RNA
Positive-Strand RNA
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Negative-Strand RNA
Negative-Strand RNA
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Protomer
Protomer
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What are Reoviruses?
What are Reoviruses?
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What are Flaviviruses?
What are Flaviviruses?
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What are Togaviruses?
What are Togaviruses?
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What are Retroviruses?
What are Retroviruses?
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What are Orthomyxoviruses?
What are Orthomyxoviruses?
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What are Paramyxoviruses?
What are Paramyxoviruses?
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What are adenoviruses?
What are adenoviruses?
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What are Picornaviruses?
What are Picornaviruses?
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What are Hepadnaviruses?
What are Hepadnaviruses?
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What are Herpesviruses?
What are Herpesviruses?
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What are Poxviruses?
What are Poxviruses?
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What are Caliciviruses?
What are Caliciviruses?
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Name the five important human herpesviruses.
Name the five important human herpesviruses.
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How can RNA viruses be classified based on their structure?
How can RNA viruses be classified based on their structure?
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What are Rhabdoviruses?
What are Rhabdoviruses?
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What are Filoviruses?
What are Filoviruses?
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What are Coronaviruses?
What are Coronaviruses?
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What is COVID-19?
What is COVID-19?
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What is SARS? (Severe Acute Respiratory Syndrome)
What is SARS? (Severe Acute Respiratory Syndrome)
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What is MERS? (Middle East Respiratory Syndrome)
What is MERS? (Middle East Respiratory Syndrome)
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What is the only human pathogen in the Rhabdovirus family?
What is the only human pathogen in the Rhabdovirus family?
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What are the two human pathogens in the Filovirus family?
What are the two human pathogens in the Filovirus family?
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What is MERS?
What is MERS?
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What is the origin of MERS-CoV?
What is the origin of MERS-CoV?
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How is MERS-CoV transmitted to humans?
How is MERS-CoV transmitted to humans?
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What is the incubation period of COVID-19?
What is the incubation period of COVID-19?
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What are the common symptoms of COVID-19?
What are the common symptoms of COVID-19?
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Who is at higher risk for severe COVID-19 symptoms?
Who is at higher risk for severe COVID-19 symptoms?
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What should you do if you suspect you have COVID-19?
What should you do if you suspect you have COVID-19?
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Study Notes
Medical Important Viruses
- Viruses are infectious agents composed minimally of a genome (RNA or DNA, but not both) and a protein capsid for protection.
- Some viruses have additional features like an envelope, a lipid bilayer with proteins.
- A complete virus particle is called a virion.
- Viruses replicate inside host cells.
- Viral pathogenicity varies greatly, even within a related virus family.
- Viruses have different sizes and structures that define viral families, genera, and species.
Virus Structure
- Viruses are significantly smaller than host cells, ranging from 20 nm to 300 nm.
- The small size allows them to pass through filters designed to trap bacteria. This lack of a cell wall is a distinguishing feature.
- Viruses can be categorized as naked (no envelope) or enveloped (with an envelope).
Virus Classification
- Viruses are classified into groups based on their genome type (DNA or RNA, single-stranded or double-stranded), genome symmetry (helical or icosahedral), and presence of an envelope.
- The Baltimore classification further categorizes viruses based on the way they produce mRNA.
Virus Replication
- Virus replication involves a series of steps including attachment to a host cell, penetration, uncoating, gene expression and replication, assembly, and release of progeny virions.
- Not all steps are the same for every virus.
- The individual steps in the viral replication cycle vary depending on the type of virus.
Viral Capsid Symmetry
- The protein shell (capsid) enclosing the viral genome can be either helical (rod-shaped) or icosahedral (spherical).
- This capsid structure is constructed from multiple copies of a single or a few different polypeptides.
Viral Envelopes
- An envelope is a lipid bilayer membrane enclosing some viruses.
- It is derived from the host cell membrane and contains viral proteins, providing virus-specific antigenicity.
- Viruses without envelopes are called naked viruses.
Viral Genomes
- Viral genomes can be DNA or RNA, single-stranded or double-stranded.
- The genome type is a major factor in virus classification.
- Viral genomes can have positive or negative polarity regarding viral direction and function within mRNA production.
Types of Viruses and Diseases
- Each type of virus causes specific diseases.
- For example, herpesviruses cause herpes, poxviruses cause smallpox.
- Various families are studied: Adenovirus, Papovavirus, Hepadnavirus, Retrovirus etc.
Molecular Tests
- Diagnostic tests include tests using nucleic acid or antibody detection to understand viral presence/activity, exposure, etc.
Covid-19
- Covid-19 is a disease caused by SARS-CoV-2.
- It displayed various symptoms, such as fever and dry cough.
- The virus replicated in a manner to produce progeny virions, infect respiratory tracts, and enter the blood stream.
- Different types of vaccines were developed based on mRNA, inactivated viruses, viral vector, or protein-based platforms.
- There are several variants of the virus, including Alpha, Beta, Gamma, Delta, and Omicron.
- Prevention involves handwashing, avoiding contact with sick people, wearing a mask, and avoiding crowded places.
Summary
- Viruses are classified based on their genome type, symmetry, and presence/absence of an envelope.
- The methods to detect and control viruses involve molecular and immunological approaches, including antibody and PCR tests.
- The various types of viruses and diseases they cause have been studied.
- The COVID-19 pandemic highlighted the role of viruses and the need for preventive measures.
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Description
Test your knowledge on the structural components of viruses and their classification! This quiz covers various aspects such as viral size, pathogenicity, and distinguishing features of different virus families. How well do you understand the complexity of viruses?