Virus Replication: Genome Classification and Replication Steps
30 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the classification property of a virus genome?

  • Method of replication
  • Genetic material (DNA or RNA) (correct)
  • Type of host cell
  • Number of strands

    • How do orthomyxoviruses and paramyxoviruses attach to cells during adsorption?

  • Through the viral genome
  • Via nuclear membrane fusion
  • Through receptor-mediated endocytosis
  • By glycoprotein spikes (correct)

    • Which type of DNA virus can exist in a circular form?

  • Single-stranded linear
  • Double-stranded circular (correct)
  • Double-stranded linear
  • Single-stranded circular

    • What process often follows penetration in viral replication?

    <p>Uncoating</p> Signup and view all the answers

    Why do viral populations not grow through cell division?

    <p>They use host cell machinery for replication</p> Signup and view all the answers

    What type of inclusion bodies are typically seen in cells infected with herpesvirus?

    <p>Nuclear inclusion bodies</p> Signup and view all the answers

    During viral replication, where do virions enter the host cell through?

    <p>Receptor-mediated endocytosis</p> Signup and view all the answers

    What is the diagnostic significance of the presence of inclusion bodies in viral infections?

    <p>Inclusion bodies are only found in some viral infections and can aid diagnosis</p> Signup and view all the answers

    Which of the following is the most accurate statement about the Negri body?

    <p>The Negri body is pathognomonic for rabies virus infection</p> Signup and view all the answers

    Which of the following is the most accurate statement about varicella (chickenpox)?

    <p>Varicella is a mild, highly contagious disease primarily affecting children</p> Signup and view all the answers

    Which of the following best describes the cytopathology of herpesviruses?

    <p>Herpesviruses cause the formation of multinucleated giant cells</p> Signup and view all the answers

    Which of the following is the most accurate statement about the diagnostic significance of inclusion bodies in viral infections?

    <p>Inclusion bodies can be useful for the diagnosis of some viral infections, but their presence is not always specific</p> Signup and view all the answers

    Which disease is characterized by a rash limited to the skin innervated by a single sensory ganglion?

    <p>Zoster (shingles)</p> Signup and view all the answers

    What is the reactivated form of an earlier varicella infection?

    <p>Shingles (Zoster)</p> Signup and view all the answers

    Which virus causes chickenpox in childhood and shingles later in life?

    <p>Varicella-Zoster virus</p> Signup and view all the answers

    What is the largest genome of all herpes viruses?

    <p>Cytomegalovirus</p> Signup and view all the answers

    Which virus has transformation of B cells as one of its associated diseases?

    <p>Epstein-Barr virus</p> Signup and view all the answers

    Which virus can only replicate in human cells and form multinucleated cells with staining inclusions?

    <p>Cytomegalovirus</p> Signup and view all the answers

    What is the approximate range of the replication cycle length for herpesviruses?

    <p>18 to 70 hours</p> Signup and view all the answers

    Which of the following is NOT mentioned as a way herpesviruses evade the immune system?

    <p>Inhibiting the production of antibodies against the virus</p> Signup and view all the answers

    What stimuli can reactivate the virus from its latent state?

    <p>Axonal injury, fever, physical or emotional stress, and exposure to ultraviolet light</p> Signup and view all the answers

    After reactivation, where does the virus replicate?

    <p>At the skin or mucous membranes</p> Signup and view all the answers

    What is true about recurrent herpesvirus infections, even in the presence of host immunity?

    <p>They are less extensive and less severe than primary infections</p> Signup and view all the answers

    What is a common manifestation of recurrent HSV-1 infection?

    <p>Cold sores (fever blisters) near the lip</p> Signup and view all the answers

    Which statement about the herpesvirus entry into host cells is correct?

    <p>The virus binds to specific cellular receptors via envelope glycoproteins and fuses with the cell membrane.</p> Signup and view all the answers

    What is the role of cellular RNA polymerase II in the herpesvirus replication cycle?

    <p>It transcribes the viral DNA throughout the replication cycle with the help of viral factors.</p> Signup and view all the answers

    Which step in the herpesvirus replication cycle involves the formation of a circular DNA molecule?

    <p>Release of viral DNA from the capsid upon entry into the host cell nucleus.</p> Signup and view all the answers

    What is the final step in the herpesvirus replication cycle before the release of new virus particles?

    <p>Transport of nucleocapsids to the cell surface through vesicular movement.</p> Signup and view all the answers

    Which herpesvirus is associated with Kaposi's sarcoma, a type of cancer?

    <p>Kaposi's sarcoma-associated herpesvirus (KSHV or HHV-8)</p> Signup and view all the answers

    Which cell type is primarily targeted by Kaposi's sarcoma-associated herpesvirus (KSHV)?

    <p>Monocytes and lymphocytes</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser